Genes and behaviour
To evaluate the contribution of various neuronal genes to the complex control of behaviour by genetic manipulation and behavioural tests in mice
Development and Disease
To understand the genetic control of mammalian development and how abnormalities in this process lead to diseases using transgenic and knockout mice
Mitochondrial Analysis
- Mitochondrial respiratory chain enzymologies in tissues including establishment of local reference ranges
- Use of various molecular techniques including next generation sequencing for the diagnosis of mitochondrial diseases and movement disorders
- Member of the International Neurotransmitter Diseases Network to set up local registry for such diseases
- Cellular consequences of mitochondrial diseases and the potential use of Chinese Medicine as therapeutic strategies in patient's cell lines
- Quality of life analysis in mitochondrial diseases and other childhood neurodegenerative diseases
