- Disease susceptibility genes of infectious and immunological diseases.
- Epidemiology of asthma and allergies, infectious diseases and common local genetic diseases, such as thalassaemia. Mannose binding lectin.
- Neonatal dendritic cell and T cell biology.
Professor Louis Chung-kai LOW
The Programme Admission Advisor
- Childhood diabetes.
- Disorders of growth and puberty.
- Iodine and thyroid dysfunction.
- Nutrition, sexual, lipids and growth.
Professor Virginia Chun-nei WONG
- Comprehensive Epilepsy programme.
- Febrile seizure project.
- Molecular genetic study on neurological disorders in Chinese , e.g. Fragile X Syndrome, Duchenne Muscular Dystrophy, Spinal Muscular atrophy. Rett Syndrome.
- Neurophysiological studies in neurodevelopmental disorders.
- Orphan disease programme.
- Traditional chinese medicine in neurohabilitation programmme.
- Comparison the adverse effects of different subcutaneous infusion sets in transfusion dependent thalassaemia patients.
- Epidemiological study on paediatric myelodysplastic syndrome.
- In vitro and in vivo studies on the use of anti-GD2 and arsenic trioxide in childhood neuroblastoma.
- In-vitro study on the effect of Reishi products towards the telomere and telomeric length in normal and malignant neurogenic cells lines.
- Use of Spectrokaryotyping and RT-PCR for the detection of recurrent chromosomal aberrations in childhood leukaemia.
- Using gene targeting technology, we have generated mice with specific expression of the EGF precursor in chondrocytes. This will allow us to dissect in more details the role of EGF in bone development and the control of body size. A student will be recruited in 2004 to work on the phenotype analysis of these mice. He/She should not live with pets in order to have access to the laboratory animal unit.
- Molecular and cellular mechanisms involved in hypoxic-ischaemic and hyperbilirubinaemic neural injuries, and motor neuron degeneration and regeneration; with emphasis on studying differential gene expressions, and adopting genetic manipulations to explore and test novel therapeutic strategies for the stated disorders.
- Molecular genetics of sexual differentiation disorders, neurodegenertive disorders, diabetes mellitus and growth disorders.
- Acoustic quantification and colour tissue Doppler in assessment of ventricular function in congenital heart defects.
- Interventional cardiac catheterization.
- Non-invasive assessment of arterial distensibility and endothelial function.
- Outcome studies of congenital heart disease.
- Experimental immunotherapy of tumours.
- Pathogenetic mechanisms of Epstein-Barr virus.
- Disease burden of influenza in children.
- Human herpes -6 & -7 infection in children.
- Streptococcus pneumoniae carriage.
- Biology of Cytokines and Interferons: signaling pathways and gene regulation.
- Immunobiology of Novel Vaccines.
- Immune Responses to Infectious Agents.
- Molecular Mechanisms of Virus- and TNF-induced Apoptosis: PKR and IRF.
Any specific question, please contact Doctor PT Cheung at the Department of Paediatrics ptcheung@hkucc.hku.hk