Dr. Winnie Wan-Yee Tso (曹蘊怡)

M.B.B.S.(London)., BSc (Hon), LMCHK, MRCPCh, FHKAM (Paed)

 

Clinical Assistant Professor
Department of
Paediatrics and Adolescent Medicine, LKS Faculty of Medicine,
The University of Hong Kong

 

 

Contact

Email:

Tel:

Fax:
Office:

wytso@hku.hk
(852) 22554482
(852) 28551523
Department of Paediatrics & Adolescent Medicine
Room 115, 1/F, New Clinical Building
102 Pokfulam Road, Queen Mary Hospital, Hong Kong

 

Research ID

ORCid: https://orcid.org/0000-0002-5859-015X

 

Research

 

Research interests: Child development & neurology

 

Dr. Tso is a developmental paediatrician with special interests in neurorehabilitation. She is a clinical assistant professor at the Department of Paediatrics & Adolescent Medicine, LKS Faculty of Medicine, University of Hong Kong. She obtained her medical degree from King’s College, University of London, United Kingdom. She has been elected as Distinguished Young Fellow by the Hong Kong College of Paediatricians in 2016 and has won numerous research awards in local as well as international scientific conferences. Dr. Tso diagnoses and manages children with developmental as well neuro-disabilities at the Queen Mary Hospital and the Duchess of Kent Children’s Hospital. She also leads the Acquired Brain Injury Program at the Duchess of Kent Children’s Hospital & Rehabilitation Centre. Her research interests include using advance imaging techniques to diagnose and manage children with developmental disabilities and brain injuries.

 

Awards:

 

Distinguished Young Fellow, elected by the Hong Kong College of Paediatricians (2016)

 

Best Dissertation Prize from the Hong Kong College of Paediatricians for the study on sleep duration and school readiness in Chinese children (Dec 2015)

 

Dolores Luiz Award from the Association for Research in Infant and Child Development (A.R.I.C.D) 16th Scientific Meeting for the presentation on Griffiths Mental Developmental Scales Validation in China. (Jan 2014)

 

Outstanding Presentation award from the Hong Kong College of Paediatricians first annual scientific meeting (Dec 2013)

 
 

Selected publications

 

Developmental Behavioral Paediatrics
1. Tso W, Chan M, Ho FK, Rao N, Li AM, Chan KL, Tiwari A, Wong ICK, Wing YK, Van Voorhees B, Li SL, Goh WHS, Ip P. Early sleep deprivation and attention-deficit/hyperactivity disorder. Pediatr Res. 2019 Jan 17. doi: 10.1038/s41390-019-0280-4. [Epub ahead of print]
2. Ip P, Tso WWY, Rao N et al. Rasch validation of the Chinese parent-child interaction scale (CPCS). World J Pediatr 2018 Jun 14(3): 238-246
3. Tso WWY, VCN Wong et al. The Griffiths Development Scales – Chinese (GDS-C): A cross cultural comparison of developmental trajectories between Chinese and British children. Child Care Health & Dev 2018; 1-6. https://doi.org/10.1111/cch.12548
4. Yeung KS*, Tso WWY*, Ip JJK et al. (* co-first authors)Identification of mutations in the PI3K-AKT-mTOR signalling pathway in patients with macrocephaly and developmental delay and/or autism. Molecular Autism (2017) 8:66 DOI 10.1186/s13229-017-0182-4
5. Ip P, Ho FKW, Rao N, Sun J, Young ME, Chow CB, Tso W, Hon KL. Impact of nutritional supplements on cognitive development of children in developing countries: A meta-analysis. Sci Rep. 2017 Sep 6;7(1):10611. doi: 10.1038/s41598-017-11023-4.
6. Tso WW, Rao N, Jiang F, Li AM, Lee SL, Ho FKW, Li SL, Ip P. Sleep duration and school readiness of Chinese Preschool Children. J Pediatr. 2016 Feb;169:266-71. doi: 10.1016/j.jpeds.2015.10.064. Epub 2015 Nov 19
7. BHY Chung, VQ Tao, WW Tso. Copy number variation and autism: new insights and clinical implications. Journal of the Formosan Medical Association. (2013) 14 March 2013

 

Child Abuse & neglect

1. Disentangling the Effects of Exposure to Maternal Substance Misuse and Physical Abuse and Neglect on Child Behavioral Problems. Wong RS, Tung KTS, Cheng AWF, Shiu YK, Wong WHS, Tso WWY, Ho MSP, Chan KL, Ho FKW, Lo CKM, Chow CB, Ip P. J Interpers Violence. 2019 May 26:886260519849661. doi: 10.1177/0886260519849661. [Epub ahead of print]
2. Prevalence of Child Maltreatment and Its Association with Parenting Style: A Population Study in Hong Kong. Lo CKM, Ho FK, Wong RS, Tung KTS, Tso WWY, Ho MSP, Chow CB, Chan KL, Ip P. Int J Environ Res Public Health. 2019 Mar 29;16(7). pii: E1130. doi: 10.3390/ijerph16071130.
3. Linking Healthcare and Social Service Databases to Study the Epidemiology of Child Maltreatment and Associated Health Problems: Hong Kong's Experience. Lo CK, Ho FK, Chan KL, Wong WH, Wong RS, Chow CB, Tsang AM, Tso WW, Ip P. J Pediatr. 2018 Nov;202:291-299.e1. doi: 10.1016/j.jpeds.2018.06.033. Epub 2018 Jul 18.
4. Lo CKM, Tung KTS, Chan KL, Yip PSF, Lau JTF, Wong WHS, Wong RS, Tsang AMC, Tsang HYH, Tso WWY, Ip P. Risk factors for child physical abuse and neglect among Chinese young mothers. Child Abuse Negl. 2017 May;67:193-206. doi: 10.1016/j.chiabu.2017.02.031.

 

Community paediatrics

1. Ip P., HO K.W., So H.K., Chan D.F., Ho S.P., Tso W.Y.W. and Nelson E.A., Socioeconomic Gradient in Childhood Obesity and Hypertension: A Multilevel Population-Based Study in a Chinese Community, PLoS One.. 2016. http://dx.doi.org/10.1371/journal.pone.0156945 (Publication No. : 261512)
2. Ip P, Chim D, Chan E.K. L, Li M. H., Ho K.W., Voorhees B.W.V., Tiwari A., Tsang A.M.C., Chan C.W.L, Ho S.P., Tso WYW, Wong WHS. Effectiveness of a Culturally attuned internet-based depression prevention program for Chinese Adolescents: A Randomized Controlled Trial, Depression and Anxiety. 2016 (Publication No. 265531)

 

Acquired brain injury

1. Tso WWY, Liu APY et al. Neurocognitive function, performance status, and quality of life in pediatric intracranial germ cell tumor survivors. Journal of Neuro-oncology 2019 Jan;141(2):393-401. doi: 10.1007/s11060-018-03045-3. Epub 2018 Nov 20.
2. WW Tso, AWY Yung, HY Lau, GCF Chan. Basal ganglia germinoma: MRI classifications correlates well with neurological and cognitive outcome. Journal of Paediatric Haematology & Oncology 2013 Sept 25

 

Medical education

1. Implementation of an interprofessional team-based learning program involving seven undergraduate health and social care programs from two universities, and students' evaluation of their readiness for interprofessional learning. Chan LK, Ganotice F Jr, Wong FKY, Lau CS, Bridges SM, Chan CHY, Chan N, Chan PWL, Chen HY, Chen JY, Chu JKP, Ho CC, Ho JMC, Lam TP, Lam VSF, Li Q, Shen JG, Tanner JA, Tso WWY, Wong AKC, Wong GTC, Wong JYH, Wong NS, Worsley A, Yu LK, Yum TP. BMC Med Educ. 2017 Nov 21;17(1):221. doi: 10.1186/s12909-017-1046-5.

Child neurology & genetics
1. Tso WW, Kwong AK, Fung CW, Wong VC. Folinic acid responsive epilepsy in Ohtahara Syndrome caused by STXBP1 mutation. Pediatric Neurology 2014 Feb: 50(2): 177-80.
2. AP Liu, WF Tang, ET Lau, KY Chan, AS Kan, KY Wong, WW Tso, K Jalal, SL Lee, CS Chau, BH Chung. Expanded Prader-Willi syndrome due to chromosome 15q11.2-14 deletion: report and a review of literature. Am J Med Genet A. 2013 Jun: 161A(6): 1309- 18

Research & Audit
Dec 2019 (Principle investigator) Effectiveness of a Technology-based Developmental Guidance Program for Enhancing Infant Mental Well-being. Grant $ 1,250,000 from Lo Ying Shek Chi Wai Foundation
Jan 2018 (Principle investigator) The structural and functional brain connectivity in children with ADHD: Relationship with disease severity and Methylphenidate treatment. Small project fund, University of Hong Kong.
Jan 2015 (Principle investigator) The use of diffusion kurtosis imaging (DKI) to quantify brain microstructure alteration as predictor for neurocognitive and functional outcomes in childhood intracranial germ cell tumour survivors.
Grant $ 630, 327- HKU RGC General Research Fund
Feb 2012 (Prinicple investigator) Genetic basis of Autism & Macrocephaly.
Grant $231,692 - Basic seeding fund from the University of Hong Kong
July 2011 (Principle investigator) Griffiths Mental Developmental Scales Validation In China (Hong Kong Centre).
Jan 2010 (Priniciple investigator) Pilot study for Re-validation of Griffiths mental developmental scales in China (Hong Kong Centre).
April 2009 (Co-investigator) Immunogenicity of pneumococcal vaccine with 3 vs. 4 schedule.    
PI: Prof YL Lau
Oct 2008 (Co-investigator) Immunogenicity of Fluvarix vaccine (GSK)    
PI: Prof YL Lau