Professor MAN Elim (文爾琳)

Prof. Elim Man
Adjunct Clinical Associate Professor
  • MBBS (HK), MD(Res) (UCL), MRes[Med] (HK), MEDM (CUHK), PgDipPD (Cardiff), MRCPCH (UK), FHKCPaed, FHKAM (Paediatrics), FRCPCH (UK), FHEA (UK)
  elimman@hku.hk
Tel: (852) 3513-6667
Fax: (852) 2855-4089
 
Research ID
Specialty
Neonatal Intensive Care
Paediatric Endocrinology
Biography
Adjunct Clinical Associate Professor, The University of Hong Kong
Honorary Clinical Associate Professor, The Chinese University of Hong Kong
Associate Director, Simulation Training Centre, Hong Kong Children’s Hospital
Associate Consultant, Department of Paediatrics & Adolescent Medicine, Hong Kong Children’s Hospital
Falcon Platoon, Hospital Authority Special Duty Cadre, HASDC
Awards
Hospital Authority CWG Corporate Scholarship (Neonatology)
Hospital Authority CWG Corporate Scholarship (Paediatric Endocrinology)
Professor Ho Hung-Chiu Medical Foundation Fellowship
BL Wong Scholarship for Master of Research in Medicine, The University of Hong Kong
Yu Chun Keung Memorial Scholarship for Master of Research in Medicine, The University of Hong Kong
Research
Areas of Interests

Neonatal Intensive Care
Necrotizing Enterocolitis
Neonatal Advanced/Point-of-Care Ultrasound, Targeted Echocardiography and Applications in Haemodynamics Monitoring

Paediatric Endocrinology
Differences of Sex Development and Adrenal Disorders

Simulation Learning and Teaching
Development and Strategies

Ongoing Territory-Wide Funded Project Coordinator:
Project Title “Hong Kong Neonatal Multi-Centred Collaborative Studies on Necrotizing Enterocolitis”
Health and Medical Research Fund (Food and Health Bureau, HKSAR) Commissioned Paediatric Research Project among eight HA NICUs, two paediatric surgery units (HKU and HKCH) and two Universities (Department of Paediatrics & Adolescent, HKU and Department of Paediatrics, CUHK)
Selected Publications
  1. Man, Elim (2022). An Investigation of Multidisciplinary Pathways in Paediatric DSD: Evaluation in Tertiary Centres in the United Kingdom and Hong Kong. Doctoral thesis (MD(Res)), UCL (University College London).
  2. Man, Elim, Imran Mushtaq, Angela Barnicoat & et al (2022). A Single-Center, Observational Study of 607 Children and Young People Presenting with Differences of Sex Development (DSD), Journal of the Endocrine Society, Volume 7, Issue 1, bvac165, https://doi.org/10.1210/jendso/bvac165
  3. Yu, F. N., Li, E. Y., Kong, C. W., Ma, T. W., Chan, K. Y., Man, E., Chung, B.H.Y. & Kan, A. S. (2021). Increasing prenatal diagnosis of chimeras with the Use of Non-invasive Prenatal Screening: Report of Two Cases. Prenatal Diagnosis. doi:10.1002/pd.5911
  4. Man, E., Peters, C., Brain, C., et al. (2021). Investigation of primary adrenal insufficiency (PAI) in children with 46,XY difference in sex development (DSD). Presented at 2021. EPSE Abstracts 94 P1-142. doi:10.1530/endoabs.45. P45.
  5. Hon, KL, Leung, Karen KY Yeung, Alexander, Man, Elim & Patrick Ip. (2020). Congenital infections in Hong Kong: Beyond TORCH. Hong Kong Medical Journal, 26(4):318-322. doi: 10.12809/hkmj208398.
  6. Leung, Karen & Hon, KL & Yeung, Alice & Leung, Alexander & Man, Elim. (2020). Congenital infections in Hong Kong: an overview of TORCH. Hong Kong Medical Journal. 26. doi:10.12809/hkmj198287.
  7. Buonocore, Federica & Clifford-Mobley, Oliver & King, Thomas & Striglioni, Niccolò & Man, Elim & Suntharalingham, Jenifer & Valle, Ignacio & Lin, Lin & Lagos, Carlos & Rumsby, Gill & Conway, Gerard & Achermann, John. (2019). Next generation sequencing reveals novel genetic variants (SRY, DMRT1, NR5A1, DHH, DHX37) in adults with 46,XY DSD. Journal of the Endocrine Society. 3. doi:10.1210/js.2019-00306.
  8. Man, E., GOSH DSD MDT., & Achermann, J.C. (2017). A single centre experience of Differences/Disorders in Sex Development (DSD) over 20 years. Presented at iDSD Symposium 2017, Copenhagen, Denmark.
  9. Man, E., Cheung, P.T., & Cheung, Y.F. (2017), Associations between arterial structure and function and serum levels of liver enzymes in obese adolescents. J Paediatr Child Health, 53: 691-697. doi:10.1111/jpc.13528
  10. Monti, E., Man, E., Torpiano, J., et al. (2016). 5-alpha reductase deficiency: insights into the diagnosis and management of a rare condition. Presented at British Society of Paediatric Endocrinology and Diabetes BSPED 2016, Nottingham, UK. Endocrine Abstracts 45 P45. doi:10.1530/endoabs.45. P45.
  11. Man, E., GOSH DSD MDT., & Achermann, J.C. (2016). A single centre experience of Differences/ Disorders in Sex Development (DSD) over 20 years. Presented at British Society of Paediatric Endocrinology and Diabetes BSPED 2016, Nottingham, UK. Endocrine Abstracts 45 OC6.9. doi:10.1530/endoabs.45.OC6.9.
  12. Man, E., Xie, L., Cheung, P. T., & Cheung, Y. F. (2015). Myocardial Integrated Backscatter in Obese Adolescents: Associations with Measures of Adiposity and Left Ventricular Deformation. PloS one, 10(10), e0141149. doi:10.1371/journal.pone.0141149.
  13. Man, E., Cheung, Y.F., & Cheung, P.T. (2015). Pre-clinical alterations in cardiovascular phenotypes and their associations with metabolic profiles among obese youths. Int J Pediatr Endocrinol, O44. doi:10.1186/1687-9856-2015-S1-O44.
  14. Man, E., Tung, Y., Luk, H., et al. (2013). A novel mutation in the SRY gene causing 46 XY complete gonadal dysgenesis in a Chinese patient. Int J Pediatr Endocrinol, P189. doi:10.1186/1687-9856-2013-S1-P189
  15. Tung, J.Y., Chan, A.O., Man, E., et al. (2013). A case of virilzing adrenocortical carcinoma diagnosed by515. 16. urine steroid profiling. Int J Pediatr Endocrinol 2013, P131. doi:10.1186/1687-9856-2013-S1-P131.
  16. Man E., Lafferty K.A., Funke B.H., et al. (2013). NGS identifies TAZ mutation in a family with X-linked dilated cardiomyopathy. BMJ Case Reports. doi: 10.1136/bcr-2012-007529.
  17. Chung, B., Man, E., Yung, T. C., et al. (2012). Identification of TAZ mutation in a family with X-linked dilated cardiomyopathy by Next Generation Sequencing. European Journal of Human Genetics, P02-250.
Book Chapter

Hughes, C.R., Man, E. and Achermann, J.C. (2020). The Adrenal Cortex and Its Disorders. In Brook's Clinical Pediatric Endocrinology, 7th Edition (eds M.T. Dattani and C.G.D. Brook). doi: 10.1002/9781119152712.ch9


Academic Reviewer

Hong Kong Journal of Paediatrics
Paediatric Obesity (up to 2019)


Teaching and Learning
Credentials
  • Fellow of Advanced Higher Education Academy in Teaching and Learning, United Kingdom
  • Professional Certificate in Teaching and Learning in Higher Education (TALIC, The University of Hong Kong; previously known as CETL)
  • Accredited Trainer of Paediatrics Specialty Trainees (Hong Kong College of Paediatricians)
  • Certified Instructor of Neonatal Lung Ultrasound Program (Shared Health Soins Communs, Manitoba), Neonatal Resuscitation Program (American Association of Paediatrics), Basic Life Support (American Heart Association)
  • Certificates in Comprehensive Simulation Educator and Debriefing Skills for Simulation Instructor Courses (HKJC ILCM)
Teaching
  • Medical undergraduates
    - Simulation Teaching Workshops for HKU MBBS and CUHK MBChB Undergraduates
    - HKCH Neonatal Teaching (Coordinator)
    - HKU MBBS Specialty Clerkship in Paediatrics
    - HKU MBBS Year IV Clinical Foundation Block Whole Class Sessions
    - HKU MBBS Examination for Paediatrics Speciality Clerkships (Examiner)
    - HKU Final MBBS Clinical Examination (Paediatrics) in 2016 (Coordinator)
  • HKU Common Core Module (CCST9064 The World Changed by DNA)
  • HKCH Simulation Training Workshops for Paediatric Trainees and Fellows (Course Co-director)
    - Neonatal Advanced Monitoring & Point-of-Care Ultrasound (POCUS) Workshops
    - Paediatric Echocardiography Workshops
    - Paediatric Electrocardiography Courses
  • Simulation Training Programs for Healthcare Professionals
    - Neonatal Resuscitation Program (American Association of Paediatrics)
    - Basic Life Support Program (American Heart Association)
    - HA Central Intern Orientation Program (Essential Clinical Skills & Safety Training Workshop Modules 1-3)
    - Paediatric Intern Learning Orientation Through Simulations (PILOTS)
    - Enhancing Sedation Safety in Children having Diagnostics & Therapeutics Procedures Course
    - HKCH Neonatal Ventilatory Therapy Simulation for Paediatric Residents, Nurses and Physiotherapists
  • Speaker in educational talks at international/local/cross-border seminars & symposiums
    - HKCH Commissioned Training in MDT DSD Care (HK, 2025), The Third Hospital of Mianyang (PRC, 2024 & 2025), University of Health Sciences (Cambodia, 2024), University of Utah (Utah, 2023), Primary Children’s Hospital (Utah, 2023), St. Vincent Healthcare, Billings (USA, 2023), HKU Shenzhen Hospital (PRC, 2022, 2023 & 2024), HKCH Commissioned Training in MDT Management of Neonatal Surgical Disorders (HK, 2019), BUHK「香港跨領域雙性人研討會」(HK, 2018), Commercial Radio HK 881903 Interview「政好星期天」(HK, 2018), Shenzhen Children’s Hospital (PRC, 2017), Copenhagen (Denmark, 2017), Amsterdam (Netherlands, 2017), London (UK, 2016), Nottingham (UK, 2016), Bologna (Italy, 2016), HKU (HK, 2015), HK PolyU (HK, 2015), Darwin (Australia, 2014), Hong Kong Youth Diabetes Action (HK, 2014, 2015), Bali (Indonesia, 2012), Hanoi (Vietnam, 2011), Dong Guan (PRC, 2006), HKU (HK, 2004) and New Orleans, Louisiana (USA, 2004)
Knowledge Exchange
Collaborations with International Academia
  • Academic administrator (by invitation) in DELPHI Consultation Rounds for UK RCPCH/CCLG guideline development projects - completed
    - Provide administrative input in DELPHI Consultation Rounds among 150 international experts in 8 rare childhood endocrine cancer categories as part of the “UK CCLG Consensus Guideline Development Projects” led by the British Society of Pediatric Endocrinology and Diabetes (BSPED), UK Children’s Cancer and Leukemia Group (CCLG) and Project Board Chair Professor Helen Spoudeaus. (See acknowledgements in “Craniopharyngioma: Guideline for the management of children and young people (CYP) aged <19 years UK: CCLG, 2021. Available from https://www.cclg.org.uk/guidelines.” and “Gan, HW., et al., National UK guidelines for the management of paediatric craniopharyngioma. Lancet Diabetes Endocrinol. 2023 Sep; 11(9):694-706. doi: 10.1016/S2213-8587(23)00162-6. Epub 2023 Aug 4. PMID: 37549682.”)
  • Academic collaborator (by invitation) in European Society of Pediatric Endocrinology (ESPE) global e-learning projects - completed
    - Collaborate with academia from various national major centers of Paediatric Endocrinology in Mainland China to carry out translation works of e-learning materials from English into Chinese Language as part of the “Development of a Global e-learning Curriculum in Pediatric Endocrinology and Diabetology for Front Line Health Care Providers in Resource-Limited Countries (RLC) project” led by the European Society of Pediatric Endocrinology (ESPE) and Professor Sten Drop. (See acknowledgements in “Kalaitzoglou E et al. Multilingual Global E-Learning Pediatric Endocrinology and Diabetes Curriculum for Front Line Health Care Providers in Resource-Limited Countries: Development Study. JMIR Form Res. 2020 Nov 5;4(11):e18555. doi: 10.2196/18555. PMID: 33151156; PMCID: PMC7677026”)
  • Academic database manager (by invitation) in DSD clinical database for the Great Ormond Street Hospital (GOSH) NHS Foundation Trust, UK - completed
    - Construct a clinical database for DSD (Differences in Sex Development) conditions by reviewing medical records of all children and young people discussed at the monthly DSD MDT meeting at GOSH over a 25-year period (1995-2019) in which analysed data was later published as one of the largest study cohorts of DSD conditions reported in the literature (see “Man, E., et al. A Single-Center, Observational Study of 607 Children and Young People Presenting With Differences of Sex Development (DSD). J Endocr Soc. 2022 Oct 28;7(1):bvac165. doi: 10.1210/jendso/bvac165. PMID: 36419940; PMCID: PMC9676112.
Community Educational Services
  • Hong Kong College of Paediatricians Foundation
    - Volunteer Medical Team Member to provide Neonatal Resuscitation Training Service (annually) for medical doctors and nurses in the rural areas of Mainland China since 2014
  • MSI (Medical Service International) Professional Services
    - Volunteer Medical Trainer in Paediatrics to provide regular professional training and online educational workshops for medical doctors, nurses and allied healthcare professionals in less-privileged areas of Mainland China, including Bichuan, Sichuan, Yunnan)
Clinical Service
Professor Man serves in the aspects below:
  • Providing specialist-led intensive and special care support for babies with surgical conditions; complex congenital and rare conditions requiring multidisciplinary inputs such as kidney failure, early gut failure, metabolic diseases, congenital heart diseases; positive screen by the HA screening program of inborn errors of metabolism (IEM), severe combined immunodeficiency (SCID) or spinal muscular atrophy (SMA); cleft lips and/or palate with feeding or airway problems at the Hong Kong Children’s Hospital
  • Providing specialist inputs as part of the multidisciplinary care of children and young people with Differences of Sex Development (DSD) at the DSD clinic of Hong Kong Children’s Hospital
  • Co-ordinating the monthly academic meeting for HKCH Hospital Grand Rounds; these are opened to all HKAM Fellows, and broadcasted to more than 20 network hospitals in Mainland China, Greater Bay Area and Macau aiming at maximizing knowledge exchange opportunities on Paediatrics-related topics through lectures, showcases, experience sharing and interactive discussions with seasonal Paediatricians and multidisciplinary members among all clinical teams at HKCH
  • Coordinating the online live broadcasting of Peking Union Medical College Hospital Rare Disease Multidisciplinary Team Case Discussion Weekly Meeting at HKCH
  • Serving member of HKCH NICU Team in hospital committees including:
    HA Cross-cluster fetal medicine-pathology-radiology-genetic (FMPRG) group; Clinical Management Committee; ECMO Service Committee; Medication Safety Committee; Non-Drug Working Group Committee; Mortuary Service Working Group Committee; Paediatrics Senior Staff Committee (Administration & Services); Paediatrics Resident Work Schedule and Planning Workgroup; Sedation Committee; Simulation Training Centre Committee
Vision in Medical Education
My teaching philosophy is to nurture students’ attitudes in inquiry for new knowledge and link professional values up with social values for application. In this paradigm, the teaching approaches and environment to nurture an independent learner/thinker (Bloom, 1956; Krathwohl, 2002) is crucial to bridge the gaps between book knowledge and practice (Singh, Bhupendra & Mishra, Patanjali, 2017). I advocate students to deepen their learning via cognitive processes, from “understanding, applying, analyzing, evaluating” and ultimately to “creating new ideas and making decisions”. In this connection, tasks/activities devised for teaching and learning are with interactive elements to motivate and enhance self-access learning strategies to assess new knowledge (Lyman, 1981) and to develop positive attitudes towards the goal of life-long learning.
It is my humble wish to endeavour a bit in the sea of medical education among young doctors. I determine to act as a facilitator, a resourceful teacher to inspire purposeful learning and accompany them along the way.