Development and Disease
To understand the genetic control of mammalian development and how abnormalities in this process lead to diseases using transgenic and knockout mice
Mitochondrial Analysis
- Mitochondrial respiratory chain enzymologies in tissues including establishment of local reference ranges
- Use of various molecular techniques including next generation sequencing for the diagnosis of mitochondrial diseases and movement disorders
- Member of the International Neurotransmitter Diseases Network to set up local registry for such diseases
- Cellular consequences of mitochondrial diseases and the potential use of Chinese Medicine as therapeutic strategies in patient's cell lines
- Quality of life analysis in mitochondrial diseases and other childhood neurodegenerative diseases