Professor Wing Hang LEUNG (梁永恆) MBBS(HK), PhD(Johns Hopkins) (leungwhf@hku.hk)
Full publications

1. Wang T, Tang Y, Cai J, Wan X, Hu S, Lu X, Xie Z, Qiao X, Jiang H, Shao J, Yang F, Ren H, Cao Q, Qian J, Zhang J, An K, Wang J, Luo C, Liang H, Miao Y, Ma Y, Wang X, Ding L, Song L, He H, Shi W, Xiao P, Yang X, Yang J, Li W, Zhu Y, Wang N, Gu L, Chen Q, Tang J, Yang JJ, Cheng C, Leung W†, Chen J†, Lu J†, Li B†, Pui CH†. Coadministration of CD19- and CD22-Directed Chimeric Antigen Receptor T-Cell Therapy in Childhood B-Cell Acute Lymphoblastic Leukemia: A Single-Arm, Multicenter, Phase II Trial. J Clin Oncol. 41(9):1670-1683, 2023. PMID: 36346962 († contributed equally)
2. Pulsipher MA, Ahn KW, Bunin NJ, Lalefar NR, Anderson EJ, Flower A, Cairo MS, Talano JA, Chaudhury S, Kitko CL, Duke JL, Monos D, Leung W, Dvorak CC, Abdel-Azim H. KIR-Favorable TCR-αβ/CD19-Depleted Haploidentical HCT in Children with ALL/AML/MDS: Primary Analysis of PTCTC ONC1401. Blood. 140(24):2556-2572, 2022. PMID: 35776909.
3. Wang H, Chan KYY, Cheng CK, Ng MHL, Lee PY, Cheng FWT, Lam GKS, Chow TW, Ha SY, Chiang AKS, Leung WH, Leung AYH, Wang CC, Zhang T, Zhang XB, So CC, Yuen YP, Sun Q, Zhang C, Xu Y, Cheung JTK, Ng WH, Tang PM, Kang W, To KF, Lee WYW, Wong RS, Poon ENY, Zhao Q, Huang J, Chen C, Yuen PMP, Li CK, Leung AWK, Leung KT. Pharmacogenomic profiling of pediatric acute myeloid leukemia to identify therapeutic vulnerabilities and inform functional precision medicine. Blood Cancer Discov. 3(6):516-535, 2022.
4. Rosa Duque JS, Wang X, Leung D, Cheng SMS, Cohen CA, Mu X, Hachim A, Zhang Y, Chan SM, Chaothai S, Kwan KKH, Chan KCK, Li JKC, Luk LLH, Tsang LCH, Wong WHS, Cheang CH, Hung TK, Lam JHY, Chua GT, Tso WWY, Ip P, Mori M, Kavian N, Leung WH, Valkenburg S, Peiris M, Tu W, Lau YL. Immunogenicity and reactogenicity of SARS-CoV-2 vaccines BNT162b2 and CoronaVac in healthy adolescents. Nat Commun. 13(1):3700, 2022. [PMCID: PMC9240007].
5. Loh AHP, Angelina C, Wong MK, Tan SH, Sukhatme SA, Yeo T, Lim SB, Lee YT, Soh SY, Leung W, Chang KTE, Chua YW, Alkaff SMF, Lim TKH, Lim CT, Chen ZX. Pro-metastatic and mesenchymal gene expression signatures characterize circulating tumor cells of neuroblastoma patients with bone marrow metastases and relapse. Front Oncol. 12:939460, 2022. [PMCID: PMC9513238].
6. Liu APY, Lam GKS, Chan WYK, Chow TTW, Cheung J, Wong SCY, Leung W, Lee PPW, Cheng FWT, Chan GCF. SARS-CoV-2 infection in children undergoing oncologic treatment in Hong Kong: A population-based cohort during the Omicron wave. Pediatr Blood Cancer. 19:e29894, 2022 [PMCID: PMC9349372]
7. Chan WYK, Ma ALT, Chan EYH, Kan ANC, Ng WF, Lee PPW, Cheuk DKL, Chiang AKS, Leung W, Chan GCF. Epidemiology and outcomes of pediatric transplant-associated thrombotic microangiopathy in Hong Kong. Pediatr Transplant. 2022 Jul 21:e14366. Epub ahead of print. PMID: 35860972.
8. Furman WL, McCarville B, Shulkin BL, Davidoff A, Krasin M, Hsu CW, Pan H, Wu J, Brennan R, Bishop MW, Helmig S, Stewart E, Navid F, Triplett B, Santana V, Santiago T, Hank JA, Gillies SD, Yu A, Sondel PM, Leung WH, Pappo A, Federico SM. Improved Outcome in Children With Newly Diagnosed High-Risk Neuroblastoma Treated With Chemoimmunotherapy: Updated Results of a Phase II Study Using hu14.18K322A. J Clin Oncol. 40(4):335-344, 2022.
9. Chua GT, Kwan MYW, Chui CSL, Smith RD, Cheung EC, Tian T, Leung MTY, Tsao SSL, Kan E, Ng WKC, Man Chan VC, Tai SM, Yu TC, Lee KP, Wong JSC, Lin YK, Shek CC, Leung ASY, Chow CK, Li KW, Ma J, Fung WY, Lee D, Ng MY, Wong WHS, Tsang HW, Kwok J, Leung D, Chung KL, Chow CB, Chan GCF, Leung WH, To KKW, Yuen KY, Lau YL, Wong ICK, Ip P. Epidemiology of Acute Myocarditis/Pericarditis in Hong Kong Adolescents Following Comirnaty Vaccination. Clin Infect Dis. 75(4):673-681, 2022
10. Mu X, Xiang Z, Xu Y, He J, Lu J, Chen Y, Wang X, Tu CR, Zhang Y, Zhang W, Yin Z, Leung WH, Lau YL, Liu Y, Tu W. Glucose metabolism controls human γδ T-cell-mediated tumor immunosurveillance in diabetes. Cell Mol Immunol. 2022 Aug;19(8):944-956, 2022. [PMCID: PMC9338301]
11. Wang X, Zhang Y, Mu X, Tu CR, Chung Y, Tsao SW, Chan GC, Leung WH, Lau YL, Liu Y, Tu W. Exosomes derived from γδ-T cells synergize with radiotherapy and preserve antitumor activities against nasopharyngeal carcinoma in immunosuppressive microenvironment. J Immunother Cancer. 10(2):e003832, 2022
12. Chan WYK, Chan NCN, So JCC, Lee PPW, Cheuk DKL, Ha SY, Chan GCF, Leung W. Successful haploidentical hematopoietic stem cell transplantation (HSCT) and durable engraftment by repeated donor lymphocyte infusions for a Chinese patient with transfusion-dependent hemoglobin (Hb) Hammersmith and massive splenomegaly. Pediatr Transplant. 26:e14278, 2022
13. Chan WYK, Lee PPW, Cheuk DKL, Yeung EWM, Wong KCW, Li CK, Chan GCF, Leung W. Blinatumomab with donor lymphocyte infusions post haploidentical hematopoietic stem cell transplantation as salvage therapy for relapsed refractory acute lymphoblastic leukemia post chimeric antigen receptor T-cell therapy. Pediatr Blood Cancer. 21:e29852, 2022.
14. Hon KLE, Leung KKY, Hui WF, Cheung WL, Leung WH. Neonatal COVID and Familial Hemophagocytic Lymphohistiocytosis. Pediatr Emerg Care. 38(3):e1094-e1096, 2022. [PMCID: PMC8884124].
15. Chua GT, Wong JSC, Chung J, Lam I, Kwong J, Leung K, Law CY, Lam CW, Kwok J, Chu PWK, Au EYL, Lam CK, Mak D, Fong NC, Leung D, Wong WHS, Ho MHK, Tsao SSL, Wong CS, Yam JC, Tso WWY, To KKW, Tam PKH, Chan GCF, Leung WH, Yuen KY, Novelli V, Klein N, Levin M, Whitaker E, Lau YL, Ip P, Kwan MYW. Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2: a case report. Hong Kong Med J. 28(1):76-78, 2022
16. Hon KL, Leung AK, Leung WH, Leung KKY, Cheong KN, Lee PP. Drugs for paediatric hyperinflammatory syndromes. Drugs Context. 11:2022-2-1, 2022. [PMCID: PMC9154350].
17. Wong JSC, Wong TS, Chua GT, Wan C, Lau SH, Ho SCS, Rosa Duque JS, Wong ICK, To KKW, Tso WWY, Wong CS, Ho MHK, Kwok J, Chow CB, Tam PKH, Chan GCF, Leung WH, Lau YL, Ip P, Kwan MYW. COVID toe in an adolescent boy: a case report. Hong Kong Med J. 2022 Mar 17.
18. Tsang HW, Chua GT, To KKW, Wong JSC, Tu W, Kwok JSY, Wong WHS, Wang X, Zhang Y, Rosa Duque JS, Chan GCF, Chu WK, Pang CP, Tam PKH, Lau YL, Wong ICK, Leung WH, Yuen KY, Kwan MYW, Ip P. Assessment of SARS-CoV-2 Immunity in Convalescent Children and Adolescents. Front Immunol. 12:797919, 2021
19. Qayed M, Ahn KW, Kitko CL, Johnson MH, Shah NN, Dvorak CC, Mellgren KM, Friend BD, Verneris MR, Leung W, Toporski J, Levine JE, Chewning JH, Wayne AS, Kapoor U, Triplett BM, Schultz KR, Yanik GA, Eapen M. A validated pediatric disease risk index for allogeneic hematopoietic cell transplantation. Blood. 137(7):983-993, 2021 [PMCID: PMC7918183]
20. Chua GT, Wong JSC, Lam I, Ho PPK, Chan WH, Yau FYS, Rosa Duque JS, Ho ACC, Siu KK, Cheung TWY, Lam DSY, Chan VCM, Lee KP, Tsui KW, Wong TW, Yau MM, Yau TY, Chan KCC, Yu MWL, Chow CK, Chiu WK, Chan KC, Wong WHS, Ho MHK, Tso WWY, Tung KTS, Wong CS, Kwok J, Leung WH, Yam JC, Wong ICK, Tam PKH, Chan GCF, Chow CB, To KKW, Lau YL, Yuen KY, Ip P, Kwan MYW. Clinical Characteristics and Transmission of COVID-19 in Children and Youths During 3 Waves of Outbreaks in Hong Kong. JAMA Netw Open. 4(5):e218824, 2021.
21. Klisovic RB, Leung WH, Brugger W, Dirnberger-Hertweck M, Winderlich M, Ambarkhane SV, Jabbour EJ. A phase 2a, single-arm, open-label study of tafasitamab, a humanized, Fc-modified, anti-CD19 antibody, in patients with relapsed/refractory B-precursor cell acute lymphoblastic leukemia. Cancer. 127(22):4190-4197, 2021.
22. Chua GT, Rosa Duque JS, Cheuk DKL, Leung AWK, Wong WHS, Liu APY, Lee PPW, Ha SY, Chiang AKS, Ho MHK, Chu WK, Chan YS, Luk CW, Ling ASC, Kwan MYW, Yiu OKF, Wong ICK, Lau YL, Li CK, Leung WH, Chan GCF, Ip P, Kwok J. HLA alleles associated with asparaginase hypersensitivity in Chinese children. J Hematol Oncol. 14(1):182, 2021.
23. Wong CH, Duque JSR, Wong JSC, Chan CV, Lam ICS, Fu YM, Cheong KN, Chua GT, Lee PP, Ip P, Ho MHK, Wong ICK, Chan GC, Leung WH, Lee SL, Lee KP, Chiu SC, Wong MSR, Wong MSC, Lau YL, Kwan MY. Epidemiology and Trends of Infective Meningitis in Neonates and Infants Less than 3 Months of Age in Hong Kong. Int J Infect Dis. 111:288-294, 2021.
24. Chan WYK, Lee PPW, Lee V, Chan GCF, Leung W, Ha SY, Cheuk DKL. Outcomes of allogeneic transplantation for hemoglobin Bart's hydrops fetalis syndrome in Hong Kong. Pediatr Transplant. 25(6):e14037, 2021.
25. Sutiman N, Nwe MS, Ni Lai EE, Lee DK, Chan MY, Eng-Juh Yeoh A, Soh SY, Leung W, Tan AM. Excellent survival outcomes of pediatric patients with acute myeloid leukemia treated with the MASPORE 2006 Protocol. Clin Lymphoma Myeloma Leuk. 21(3):290-300, 2021
26. Leung W, Soh TG, Linn YC, Low JG, Loh J, Chan M, Chng WJ, Koh LP, Poon ML, Ng KP, Kuick CH, Tan TT, Tan LK, Seng MS.
    Rapid production of clinical-grade SARS-CoV-2 specific T cells. Adv Cell Gene Ther. e101, 2020. [PMCID: PMC7404427]
27. He Y, Jiang H, Li C, Zhu Y, Wu X, Liu S, Qu Y, Liao J, Feng X, Liu H, Peng Z, He L, Pu C, Gautam M, Leung W, Li C.
    Long-term Results of the NF-08-TM Protocol in Stem Cell Transplant for Patient with Thalassemia Major: A Multi-center Large-sample Study. Am J Hematol. 2020. doi: 10.1002/ajh.25969.
28. Davies SM, Iannone R, Alonzo TA, Wang YC, Gerbing R, Soni S, Kolb EA, Meshinchi S, Orchard PJ, Burns LJ, Shenoy S, Leung W.
    A Phase 2 Trial of KIR-Mismatched Unrelated Donor Transplantation Using in Vivo T Cell Depletion with Antithymocyte Globulin in Acute Myelogenous Leukemia: Children's Oncology Group AAML05P1 Study. Biol Blood Marrow Transplant. 26(4):712-717, 2020. [PMCID: PMC7198330]
29. Nguyen R, Sahr N, Sykes A, McCarville MB, Federico SM, Sooter A, Cullins D, Rooney B, Janssen WE, Talleur AC, Triplett BM, Anthony G, Dyer MA, Pappo AS, Leung W, Furman WL.
    Longitudinal NK Cell Kinetics and Cytotoxicity in Children With Neuroblastoma Enrolled in a Clinical Phase II Trial. J Immunother Cancer. 8(1):e000176, 2020. [PMCID: PMC7206969]
30. Mamcarz E, Madden R, Qudeimat A, Srinivasan A, Talleur A, Sharma A, Suliman A, Maron G, Sunkara A, Kang G, Leung W, Gottschalk S, Triplett BM.
    Improved survival rate in T-cell depleted haploidentical hematopoietic cell transplantation over the last 15 years at a single institution. Bone Marrow Transplant. 55(5):929-938, 2020. [PMCID: PMC7202974]
31. Wang YM, Anderson E, Gloude N, Marion A, King C, Leung W, Schiff D.
    Irradiation-free RIC HSCT has a tolerable safety profile and is effective therapy for pediatric bone marrow failure syndromes. Pediatr Transplant. 2020 Oct 6:e13855. doi: 10.1111/petr.13855. Epub ahead of print. PMID: 33022813.
32. Kjellin M, Qudeimat A, Browne E, Keerthi D, Sunkara A, Kang G, Winfield A, Giannini MA, Maron G, Hayden R, Leung W, Triplett B, Srinivasan A.
    Effectiveness of Bath Wipes After Hematopoietic Cell Transplantation: A Randomized Trial. J Pediatr Oncol Nurs. 37(6):390-397, 2020.
33. Furman WL, Federico SM, McCarville MB, Shulkin BL, Davidoff AM, Krasin MJ, Sahr N, Sykes A, Wu J, Brennan RC, Bishop MW, Helmig S, Stewart E, Navid F, Triplett B, Santana VM, Bahrami A, Anthony G, Yu AL, Hank J, Gillies SD, Sondel PM, Leung W, Pappo AS.
    A Phase II Trial of Hu14.18K322A in Combination with Induction Chemotherapy in Children with Newly Diagnosed High-Risk Neuroblastoma. Clin Cancer Res. 25(21):6320-6328, 2019. [PMCID: PMC6825564]
34. Bari R, Granzin M, Tsang KS, Roy A, Krueger W, Orentas R, Pfeifer R, Moeker N, Verhoeyen E, Dropulic B, Leung W.
    A Distinct Subset of Highly Proliferative and Lentiviral Vector (LV)-Transducible NK Cells Define a Readily Engineered Subset for Adoptive Cellular Therapy. Front Immunol. 10:2001, 2019. [PMCID: PMC6713925].
35. Talleur AC, Métais JY, Li Y, Throm RE, Tillman H, Rooney B, Moustaki A, Leung W.
    Allogeneic CD27‐depleted cells in adoptive cell therapy. Adv Cell Gene Ther. 2:45, 2019
36. Nguyen R, Wu H, Pounds S, Inaba H, Ribeiro RC, Cullins D, Rooney B, Bell T, Lacayo NJ, Heym K, Degar B, Schiff D, Janssen WE, Triplett B, Pui CH, Leung W, Rubnitz JE.
    A phase II clinical trial of adoptive transfer of haploidentical natural killer cells for consolidation therapy of pediatric acute myeloid leukemia. J Immunother Cancer. 7:81, 2019
37. Triplett BM, Muller B, Kang G, Ying L, Cross SJ, Moen J, Cunningham L, Janssen W, Mamcarz E, Shook DR, Srinivasan A, Choi J, Hayden RT, Leung W.
    Selective T-cell depletion targeting CD45RA reduces viremia and enhances early T-cell recovery compared to CD3-targeted T-cell depletion. Transpl Infect Dis. 20:12823, 2018. [PMCID: PMC5809307]
38. Nemecek ER, Hilger RA, Adams A, Shaw BE, Kiefer D, Le-Rademacher J, Levine JE, Yanik G, Leung W, Talano JA, Haut P, Delgado D, Kapoor N, Petrovic A, Adams R, Hanna R, Rangarajan H, Dalal J, Chewning J, Verneris MR, Epstein S, Burroughs L, Perez-Albuerne ED, Pulsipher MA, Delaney C.
    Treosulfan, fludarabine, and low-dose total body irradiation for children and young adults with acute myeloid leukemia or myelodysplastic syndrome undergoing allogeneic hematopoietic cell transplantation: prospective phase II trial of the Pediatric Blood and Marrow Transplant Consortium. Biol Blood Marrow Transplant. 24(8):1651-1656, 2018
39. Gilman AL, Leung W, Cowan MJ, Cannon M, Epstein S, Barnhart C, Shah K, Hyland M, Fukes T, Ivanova A.
    Donor lymphocyte infusion and methotrexate for immune recovery after T-cell depleted haploidentical transplantation. Am J Hematol. 93(2):169-178, 2018
40. Talleur AC, Triplett BM, Federico S, Mamcarz E, Janssen W, Wu J, Shook D, Leung W, Furman WL.
    Consolidation therapy for newly diagnosed pediatric patients with high-risk neuroblastoma using busulfan/melphalan, autologous hematopoietic cell transplantation, anti-GD2 antibody, granulocyte-macrophage colony-stimulating factor, interleukin-2, and haploidentical natural killer cells. Biol Blood Marrow Transplant. 23(11):1910-1917, 2017
41. Federico SM, McCarville MB, Shulkin BL, Sondel PM, Hank JA, Hutson P, Meagher M, Shafer A, Ng CY, Leung W, Janssen WE, Wu J, Mao S, Brennan RC, Santana VM, Pappo AS, Furman WL.
    A pilot trial of humanized anti-GD2 monoclonal antibody (hu14.18k322a) with chemotherapy and natural killer cells in children with recurrent/refractory neuroblastoma. Clin Cancer Res. 23(21):6441 -6449, 2017
42. Fernández L, Metais JY, Escudero A, Vela M, Valentín J, Vallcorba I, Leivas A, Torres J, Valeri A, Patiño-García A, Martínez J, Leung W, Pérez-Martínez A.
    Memory t cells expressing an NKG2D-CAR efficiently target osteosarcoma cells. Clin Cancer Res. 23(19):5824-5835, 2017
43. Liao J, Sylla G, He Y, Leung W, Liu X, Chen J, Peng Z, Pei F, Li N, Ren Y, Feng X, Wu X, Li C.
    Successful engraftment determined by the quality rather than quantity of the haematopoietic graft: a lesson from co-transplantation of unrelated cord blood and mobilized haploidentical peripheral blood in monozygotic twins. Br J Haematol. 179(4):677-679, 2017
44. Pui CH, Pei D, Raimondi SC, Coustan-Smith E, Jeha S, Cheng C, Bowman WP, Sandlund JT, Ribeiro RC, Rubnitz JE, Inaba H, Gruber TA, Leung W, Yang JJ, Downing JR, Evans WE, Relling MV, Campana D.
    Clinical impact of minimal residual disease in children with different subtypes of acute lymphoblastic leukemia treated with response-adapted therapy. Leukemia. 31(2):333-339, 2017
45. Bari R, Thapa R, Bao J, Li Y, Zheng J, Leung W.
    KIR2DL2/2DL3-E(35) alleles are functionally stronger than -Q(35) alleles. Sci Rep. 6:23689, 2016. [PMCID: PMC4814820]
46. Al Malki MM, Horowitz M, Handgretinger R, Leung W, Roy DC, Huang XJ, Fuchs E, Locatelli F, Blaise D, Mineishi S, Martelli M, Miller J, June C, Ai HS, Luznik L, Mavilio D, Lugli E, van den Brink MR, Champlin RE, Ciurea SO.
    Proceedings from the Second Haploidentical Stem Cell Transplantation Symposium-Haplo2014. Biol Blood Marrow Transplant. 22(4):594-604, 2016
47. Koehl U, Kalberer C, Spanholtz J, Lee DA, Miller JS, Cooley S, Lowdell M, Uharek L, Klingemann H, Curti A, Leung W, Alici E.
    Advances in clinical NK cell studies: Donor selection, manufacturing and quality control. Oncoimmunology. 5(4):e1115178, 2016
48. Leung WH, Vong QP, Lin W, Bouck D, Wendt S, Sullivan E, Li Y, Bari R, Chen T, Leung W.
    PRL-3 Mediates the Protein Maturation of ULBP2 by Regulating the Tyrosine Phosphorylation of HSP60. J Immunol. 194(6):2930-41, 2015 [PMCID:PMC4355089]
49. Chan WK, Suwannasaen D, Throm RE, Li Y, Eldridge PW, Houston J, Gray JT, Pui CH, Leung W.
    Chimeric antigen receptor-redirected CD45RA-negative T cells have potent antileukemia and pathogen memory response without graft-versus-host activity. Leukemia. 29(2):387-95, 2015 [PMCID:PMC4275423]
50. Bari R, Hartford C, Keung Chan W, Vong Q, Li Y, Gan K, Zhou Y, Cheng C, Kang G, Shurtleff S, Turner V, Pui CH, Downing JR, Leung W.
    Genome-wide single-nucleotide polymorphism analysis revealed SUFU suppression of acute graft-versus-host disease through downregulation of HLA-DR expression in recipient dendritic cells. Sci Rep. 5:11098, 2015. [PMCID: PMC4464079]
51. Triplett BM, Kuttab HI, Kang G, Leung W.
    Escalation to High-Dose Defibrotide in Patients with Hepatic Veno-Occlusive Disease. Biol Blood Marrow Transplant. 21(12):2148-53, 2015 [PMCID: PMC4639417]
52. Rubnitz JE, Inaba H, Kang G, Gan K, Hartford C, Triplett BM, Dallas M, Shook D, Gruber T, Pui CH, Leung W.
    Natural killer cell therapy in children with relapsed leukemia. Pediatr Blood Cancer. 62(8):1468-72, 2015
53. Shook DR, Triplett BM, Eldridge PW, Kang G, Srinivasan A, Leung W.
    Haploidentical stem cell transplantation augmented by CD45RA negative lymphocytes provides rapid engraftment and excellent tolerability. Pediatr Blood Cancer. 62(4):666-73, 2015
54. Hayden RT, Gu Z, Liu W, Lovins R, Kasow K, Woodard P, Srivastava K, Leung W.
    Risk factors for hemorrhagic cystitis in pediatric allogeneic hematopoietic stem cell transplant recipients. Transpl Infect Dis. 17(2):234-41, 2015.
55. Mullighan CG, Jeha S, Pei D, Payne-Turner D, Coustan-Smith E, Roberts KG, Waanders E, Choi JK, Ma X, Raimondi SC, Fan Y, Yang W, Song G, Yang JJ, Inaba H, Downing JR, Leung W, Bowman WP, Relling MV, Evans WE, Zhang J, Campana D, Pui CH.
    Outcome of children with hypodiploid ALL treated with risk-directed therapy based on MRD levels. Blood. 126(26):2896-9, 2015. [PMCID: PMC4692147]
56. Fernández L, Valentín J, Zalacain M, Leung W, Patiño-García A, Pérez-Martínez A.
    Activated and expanded natural killer cells target osteosarcoma tumor initiating cells in an NKG2D-NKG2DL dependent manner. Cancer Lett. 368(1):54-63, 2015.
57. Burke MJ, Verneris MR, Le Rademacher J, He W, Abdel-Azim H, Abraham AA, Auletta JJ, Ayas M, Brown VI, Cairo MS, Chan KW, Diaz Perez MA, Dvorak CC, Egeler RM, Guilcher GM, Hayashi RJ, Kasow KA, Leung W, Olsson RF, Pulsipher MA, Shah NN, Thiel E, Kitko CL.
    Transplant Outcomes for Children with T Cell Acute Lymphoblastic Leukemia in Second Remission: A Report from the Center for International Blood and Marrow Transplant Research. Biol Blood Marrow Transplant. 21(12):2154-9, 2015. [PMCID: PMC4654112]
58. Pui CH, Pei D, Coustan-Smith E, Jeha S, Cheng C, Bowman WP, Sandlund JT, Ribeiro RC, Rubnitz JE, Inaba H, Bhojwani D, Gruber TA, Leung W, Downing JR, Evans WE, Relling MV, Campana D.
    Clinical utility of sequential minimal residual disease measurements in the context of risk-based therapy in childhood acute lymphoblastic leukaemia: a prospective study. Lancet Oncol. 16(4):465-74, 2015
59. Bi W, Kang G, Zhao Y, Cui Y, Yan S, Li Y, Cheng C, Pounds SB, Borowitz MJ, Relling MV, Yang JJ, Liu Z, Pui CH, Hunger SP, Hartford CM, Leung W, Zhang JF.
    SVSI: Fast and Powerful Set-Valued System Identification Approach to Identifying Rare Variants in Sequencing Studies for Ordered Categorical Traits. Ann Hum Genet. 79(4):294-309, 2015. [PMCID: PMC4474746].
60. Mehta PA, Zhang MJ, Eapen M, He W, Seber A, Gibson B, Camitta BM, Kitko CL, Dvorak CC, Nemecek ER, Frangoul HA, Abdel-Azim H, Kasow KA, Lehmann L, Vicent MG, Diaz Pérez MA, Ayas M, Qayed M, Carpenter PA, Jodele S, Lund TC, Leung W, Davies SM.
    Transplantation Outcomes for Children with Hypodiploid Acute Lymphoblastic Leukemia. Biol Blood Marrow Transplant. 21(7):1273-7, 2015. [PMCID: PMC4465998].
61. Veys PA, Nanduri V, Baker KS, He W, Bandini G, Biondi A, Dalissier A, Davis JH, Eames GM, Egeler RM, Filipovich AH, Fischer A, Jürgens H, Krance R, Lanino E, Leung W, Matthes S, Michel G, Orchard PJ, Pieczonka A, Ringdén O, Schlegel PG, Sirvent A, Vettenranta K, Eapen M.
    Haematopoietic stem cell transplantation for refractory Langerhans cell histiocytosis: outcome by intensity of conditioning. Br J Haematol. 169(5):711-8, 2015. [PMCID: PMC4433436].
62. Kaste SC, Kaufman RA, Sunkara A, Kang G, Morris C, Leung W, Srinivasan A.
    Routine Pre- and Post-Hematopoietic Stem Cell Transplant Computed Tomography of the Abdomen for Detecting Invasive Fungal Infection Has Limited Value. Biol Blood Marrow Transplant. 21(6):1132-5, 2015
63. Williams-Hooker R, Adams M, Havrilla DA, Leung W, Roach RR, Mosby TT.
    Caregiver and health care provider preferences of nutritional support in a hematopoietic stem cell transplant unit. Pediatr Blood Cancer. 62(8):1473-6, 2015
64. Srinivasan A, Klepper C, Sunkara A, Kang G, Carr J, Gu Z, Leung W, Hayden RT.
    Impact of Adenoviral Stool Load on Adenoviremia in Pediatric Hematopoietic Stem Cell Transplant Recipients. Pediatr Infect Dis J. 34(6):562-5, 2015
65. Tomchuck SL, Leung W, Dallas MH.
    Enhanced Cytotoxic Function of Natural Killer and CD3(+)CD56(+) Cells in Cord Blood after Culture. Biol Blood Marrow Transplant. 21(1):39-49, 2015
66. Perko R, Kang G, Sunkara A, Leung W, Thomas PG, Dallas MH.
    Gamma delta T cell reconstitution is associated with fewer infections and improved event-free survival after hematopoietic stem cell transplantation for pediatric leukemia. Biol Blood Marrow Transplant. 21(1):130-6, 2015.
67. Karol SE, Coustan-Smith E, Cao X, Shurtleff SA, Raimondi SC, Choi JK, Ribeiro RC, Dahl GV, Bowman WP, Taub JW, Degar B, Leung W, Downing JR, Pui CH, Rubnitz JE, Campana D, Inaba H.
    Prognostic factors in children with acute myeloid leukaemia and excellent response to remission induction therapy. Br J Haematol. 168(1):94-101, 2015
68. Srinivasan A, Srinivasan S, Sunthankar S, Sunkara A, Kang G, Stokes DC, Leung W.
    Pre-hematopoietic stem cell transplant lung function and pulmonary complications in children. Ann Am Thorac Soc. 11(10):1576-85, 2014
69. Vong QP, Leung WH, Houston J, Li Y, Rooney B, Holladay M, Oostendorp R, Leung W.
    TOX2 regulates human natural killer cell development by controlling T-BET expression. Blood. 124(26):3905-13, 2014 [PMCID:PMC4282154]
70. Sullivan EM, Jeha S, Kang G, Cheng C, Rooney B, Holladay M, Bari R, Schell S, Tuggle M, Pui CH, Leung W.
    NK Cell Genotype and Phenotype at Diagnosis of Acute Lymphoblastic Leukemia Correlate to Post-induction Residual Disease. Clin Cancer Res. 20(23):5986-94, 2014 [PMCID:PMC4252745]
71. Srinivasan A, Panetta JC, Cross SJ, Pillai A, Triplett BM, Shook DR, Dallas MH, Hartford C, Sunkara A, Kang G, Jacobsen J, Choi J, Leung W.
    Phase I study of the safety and pharmacokinetics of plerixafor in children undergoing a second allogeneic hematopoietic stem cell transplantation for relapsed or refractory
    leukemia. Biol Blood Marrow Transplant. 20(8):1224-8, 2014
72. Willard VW, Leung W, Huang Q, Zhang H, Phipps S.
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73. Roberts KG, Pei D, Campana D, Payne-Turner D, Li Y, Cheng C, Sandlund JT, Jeha S, Easton J, Becksfort J, Zhang J, Coustan-Smith E, Raimondi SC, Leung W, Relling MV, Evans WE, Downing JR, Mullighan CG, Pui CH.
    Outcomes of Children With BCR-ABL1-Like Acute Lymphoblastic Leukemia Treated With Risk-Directed Therapy Based on the Levels of Minimal Residual Disease. J Clin Oncol. 32(27):3012-20, 2014
74. Karski EE, Dvorak CC, Leung W, Miller W, Shaw PJ, Qayed M, Katsanis E, Feusner JH.
    Treatment of Hepatoblastoma With High-dose Chemotherapy and Stem Cell Rescue: The Pediatric Blood and Marrow Transplant Consortium Experience and Review of the Literature. J Pediatr Hematol Oncol. 36(5):362-8, 2014.
75. Srinivasan A, McLaughlin L, Wang C, Srivastava DK, Shook DR, Leung W, Hayden RT.
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76. Rubnitz JE, Inaba H, Leung W, Pounds S, Cao X, Campana D, Ribeiro RC, Pui CH.
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77. Pui CH, Pei D, Campana D, Cheng C, Sandlund JT, Bowman WP, Hudson MM, Ribeiro RC, Raimondi SC, Jeha S, Howard SC, Bhojwani D, Inaba H, Rubnitz JE, Metzger ML,  Gruber TA, Coustan-Smith E, Downing JR, Leung WH, Relling MV, Evans WE.
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78. Srinivasan A, Wang WC, Gaur A, Smith T, Gu Z, Kang G, Leung W, Hayden RT.
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79. Leung WH, Vong QP, Lin W, Janke L, Chen T, Leung W.
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80. Bari R, Rujkijyanont P, Sullivan E, Kang G, Turner V, Gan K, Leung W.
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81. Rujkijyanont P, Morris C, Kang G, Gan K, Hartford C, Triplett B, Dallas M, Srinivasan A, Shook D, Pillai A, Pui CH, Leung W.
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82. Chan WK, Rujkijyanont P, Neale G, Yang J, Bari R, Das Gupta N, Holladay M, Rooney B, Leung W.
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83. Dallas MH, Triplett B, Shook DR, Hartford C, Srinivasan A, Laver J, Ware R, Leung W.
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84. Rujkijyanont P, Chan WK, Eldridge PW, Lockey T, Holladay M, Rooney B, Davidoff AM, Leung W, Vong Q.
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85. Shook DR, Triplett BM, Srinivasan A, Hartford C, Dallas MH, Pillai A, Laver J, Leung W.
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86. Sandlund JT, Shurtleff SA, Onciu M, Horwitz E, Leung W, Howard V, Rencher R, Conley ME.
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87. Gadalla SM, Sales-Bonfim C, Carreras J, Alter BP, Antin JH, Ayas M, Bodhi P, Davis J, Davies SM, Deconinck E, Deeg HJ, Duerst RE, Fasth A, Ghavamzadeh A, Giri N, Goldman FD, Kolb EA, Krance R, Kurtzberg J, Leung WH, Srivastava A, Or R, Richman CM, Rosenberg PS, Toledo Codina JS, Shenoy S, Socié G, Tolar J, Williams  KM, Eapen M, Savage SA.
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88. Srinivasan A, Gu Z, Smith T, Morgenstern M, Sunkara A, Kang G, Srivastava DK, Gaur AH, Leung W, Hayden RT.
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89. Srinivasan A, Flynn P, Gu Z, Hartford C, Lovins R, Sunkara A, Srivastava DK, Leung W, Hayden RT.
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90. Navid F, Baker SD, McCarville MB, Stewart CF, Billups CA, Wu J, Davidoff AM, Spunt S, Furman WL, McGregor LM, Hu S, Panetta J, Turner D, Fofana D, Reddick WE, Leung W, Santana VM.
    Phase I and Clinical Pharmacology Study of Bevacizumab, Sorafenib, and Low-dose Cyclophosphamide in Children and Young Adults with Refractory/Recurrent Solid Tumors. Clin Cancer Res. 19(1):236-46, 2013. [PMCID: PMC3537913].
91. Srinivasan A, Wang C, Srivastava DK, Burnette K, Shenep JL, Leung W, Hayden RT.
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92. Leung W, Pui CH, Coustan-Smith E, Yang J, Pei D, Gan K, Rubnitz JE, Sandlund JT, Ribeiro RC, Srinivasan A, Hartford C, Triplett BM, Dallas M, Pillai A, Handgretinger R, Laver JH, Campana D.
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93. Inaba H, Yang J, Kaste SC, Hartford CM, Motosue MS, Chemaitilly W, Triplett BM, Shook DR, Pui CH, Leung W.
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94. Chan WK, Kung Sutherland M, Li Y, Zalevsky J, Schell S, Leung W.
    Antibody-Dependent Cell-Mediated Cytotoxicity Overcomes NK Cell Resistance in MLL-Rearranged Leukemia Expressing Inhibitory KIR Ligands but Not Activating Ligands. Clin Cancer Res. 18(22):6296-305, 2012. [PMCID: PMC3500445]
95. Triplett BM, Wang C, Yang J, Dallas M, Hartford C, Howard V, Pillai A, Shook D, Srinivasan A, Laver J, Leung W.
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96. Srinivasan A, Kasow KA, Cross S, Parrish M, Wang C, Srivastava DK, Cai X, Panetta JC, Leung W.
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97. Rujkijyanont P, Hipps J, Gan K, Yang J, Wang C, Geiger TL, Eldridge PW, Leung W.
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98. Inaba H, Hartford CM, Pei D, Posner MJ, Yang J, Hayden RT, Srinivasan A, Triplett BM, McCulllers JA, Pui CH, Leung W.
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99. Inaba H, Coustan-Smith E, Cao X, Pounds SB, Shurtleff SA, Wang KY, Raimondi SC, Onciu M, Jacobsen J, Ribeiro RC, Dahl GV, Bowman WP, Taub JW, Degar B, Leung W, Downing JR, Pui CH, Rubnitz JE, Campana D.
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100. Pui CH, Pei D, Pappo AS, Howard SC, Cheng C, Sandlund JT, Furman WL, Ribeiro RC, Spunt SL, Rubnitz JE, Jeha S, Hudson MM, Kun LE, Merchant TE, Kocak M, Broniscer A, Metzger ML, Downing JR, Leung W, Evans WE, Gajjar A.
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101. Veys P, Wynn RF, Ahn KW, Samarasinghe S, He W, Bonney D, Craddock J, Cornish J, Davies SM, Dvorak CC, Duerst RE, Gross TG, Kapoor N, Kitko C, Krance RA, Leung W, Lewis VA, Steward C, Wagner JE, Carpenter PA, Eapen M.
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102. Shimasaki N, Fujisaki H, Cho D, Masselli, Lockey T, Eldridge P, Leung W, Campana D.
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103. Kasow KA, Stewart CF, Barfield RC, Wright NL, Li C, Srivastava DK, Leung W, Horwitz EM, Bowman LC, Handgretinger R, Hale GA.
     A phase I/II study of CY and topotecan in patients with high-risk malignancies undergoing autologous hematopoietic cell transplantation: the St Jude long-term follow-up. Bone Marrow Transplant. 47(11):1448-54, 2012.
104. Sharma S, Leung W, Deqing P, Yang J, Rochester R, Britton L, Neel MD, Ness KK, Kaste SC.
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105. Inaba H, Bhojwani D, Pauley JL, Pei D, Cheng C, Metzger ML, Howard SC, Rubnitz JE, Sandlund JT, Ribeiro RC, Leung W, Campana D, Pui CH, Jeha S.
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106. Bhojwani D, Pei D, Sandlund JT, Jeha S, Ribeiro RC, Rubnitz JE, Raimondi SC, Shurtleff S, Onciu M, Cheng C, Coustan-Smith E, Bowman WP, Howard SC, Metzger ML, Inaba H, Leung W, Evans WE, Campana D, Relling MV, Pui CH.
     ETV6-RUNX1-positive childhood acute lymphoblastic leukemia: improved outcome with contemporary therapy. Leukemia. 26(2):265-70, 2012 [PMCID: PMC3345278]
107. Leung W, Campana D, Yang J, Pei D, Coustan-Smith E, Gan K, Rubnitz JE, Sandlund JT, Ribeiro RC, Srinivasan A, Hartford C, Triplett BM, Dallas M, Pillai A, Handgretinger R, Laver JH, Pui CH.
     High success rate of hematopoietic cell transplantation regardless of donor source in children with very high-risk leukemia. Blood. 118(2):223-30, 2011 [PMCID: PMC3138677]
108. Pillai A, Hartford C, Wang C, Yang J, Srinivasan A, Triplett B, Dallas M, Leung W.
     Favorable preliminary results using TLI/ATG-based immunomodulatory conditioning for matched unrelated donor allogeneic hematopoietic stem cell transplantation in pediatric severe aplastic anemia. Pediatr Transplant. 15(6):628-34, 2011
109. Bari R, Leung M, Turner VE, Embrey C, Rooney B, Holladay M, Leung W
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110. Perez-Martinez A, Iyengar R, Gan K, Chotsampancharoen T, Rooney B, Holladay M, Ramírez M, Leung W.
     Blood dendritic cells suppress NK cell function and increase the risk of leukemia relapse after hematopoietic cell transplantation. Biol Blood Marrow Transplant. 17(5): 598-607, 2011 [PMCID: PMC3047596]
111. Mosby TT, Griffith LK, Jones M, Allen G, Yang J, Wang C, Leung W, Williams R.
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112. Srinivasan A, Wang C, Yang J, Inaba H, Shenep JL, Leung W, Hayden RT.
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113. Srinivasan A, Wang C, Yang J, Shenep JL, Leung W, Hayden RT.
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114. Pui CH, Pei D, Campana D, Bowman WP, Sandlund JT, Kaste SC, Ribeiro RC, Rubnitz JE, Coustan-Smith E, Jeha S, Cheng C, Metzger ML, Bhojwani D, Inaba H, Raimondi SC, Onciu M, Howard SC, Leung W, Downing JR, Evans WE, Relling MV.
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115. Sharma S, Yang S, Rochester R, Britton L, Leung W, Yang J, Neel MD, Ness KK, Kaste SC.
     Prevalence of osteonecrosis and associated risk factors in children before allogeneic BMT. Bone Marrow Transplant. 46(6):813-9, 2011 [PMCID: PMC3010322]
116. Leung W, Neale G, Behm F, Iyengar R, Finkelstein D, Kastan MB, Pui CH.
     Deficient innate immunity, thymopoiesis, and gene expression response to radiation in survivors of childhood acute lymphoblastic leukemia. Cancer Epidemiol. 34(3):303-8, 2010 [PMCID: PMC2874127]
117. Inaba H, Yang J, Pan J, Stokes DC, Krasin MJ, Srinivasan A, Hartford CM, Pui CH, Leung W.
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118. Rubnitz JE, Inaba H, Ribeiro RC, Pounds S, Rooney B, Bell T, Pui CH, Leung W.
     NKAML: A pilot study of haploidentical natural killer cell transplantation in childhood acute myeloid leukemia. J Clin Oncol 28(6):955-9, 2010 [PMCID: PMC2834435]
119. Shaw PJ, Kan F, Woo Ahn K, Spellman SR, Aljurf M, Ayas M, Burke M, Cairo MS, Chen AR, Davies SM, Frangoul H, Gajewski J, Gale RP, Godder K, Hale GA, Heemskerk MB, Horan J, Kamani N, Kasow KA, Chan KW, Lee SJ, Leung W, Lewis VA, Miklos D, Oudshoorn M, Petersdorf EW, Ringdén O, Sanders J, Schultz KR, Seber A, Setterholm M, Wall DA, Yu L, Pulsipher MA.
     Outcomes of pediatric bone marrow transplantation for leukemia and myelodysplasia using matched sibling, mismatched related, or matched unrelated donors. Blood. 116(19):4007-15, 2010
120. Broniscer A, Baker JN, Tagen M, Onar-Thomas A, Gilbertson RJ, Davidoff AM, Panandiker AP, Leung W, Chin TK, Stewart CF, Kocak M, Rowland C, Merchant TE, Kaste SC, Gajjar A.
     Phase I study of vandetanib during and after radiotherapy in children with diffuse intrinsic pontine glioma. J Clin Oncol. 28(31):4762-8, 2010 [PMCID: PMC3020706]
121. Rubnitz JE, Inaba H, Dahl G, Ribeiro RC, Bowman WP, Taub J, Pounds S, Razzouk BI, Lacayo NJ, Cao X, Meshinchi S, Degar B, Airewele G, Raimondi SC, Onciu M, Coustan-Smith E, Downing JR, Leung W, Pui CH, Campana D.
     Minimal residual disease-directed therapy for childhood acute myeloid leukaemia: results of the AML02 multicentre trial. Lancet Oncol. 11(6):543-52, 2010 [PMCID: PMC3171799]
122. Bari R, Bell T, Leung WH, Vong QP, Chan WK, Dasgupta N, Holladay M, Rooney B, Leung W.
     Significant functional heterogeneity among KIR2DL1 alleles and a pivotal role of arginine245. Blood 114(25):5182-90, 2009 [PMCID: PMC2792213]
123. Triplett BM, Horwitz EM, Iyengar R, Turner V, Holladay M, Gan K, Behm FG, Leung W.
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124. Chotsampancharoen T, Gan K, Kasow KA, Barfield RC, Hale GA, Leung W.
     Iron overload in survivors of childhood leukemia after allogeneic hematopoietic stem cell transplantation. Pediatr Transplant 13(3):348-52, 2009
125. Pui CH, Campana D, Pei D, Bowman WP, Sandlund JT, Kaste SC, Ribeiro RC, Rubnitz JE, Raimondi SC, Onciu M, Coustan-Smith E, Kun LE, Jeha S, Cheng C, Howard SC, Simmons V, Bayles A, Metzger ML, Boyett JM, Leung W, Handgretinger R, Downing JR, Evans WE, Relling MV.
     Treating childhood acute lymphoblastic leukemia without cranial irradiation. N Engl J Med 360(26):2730-41, 2009 [PMCID: PMC2754320]
126. Fujisaki H, Kakuda H, Shimasaki N, Imai C, Ma J, Lockey T, Eldridge P, Leung W, Campana D.
     Expansion of Highly Cytotoxic Human Natural Killer Cells for Cancer Cell Therapy. Cancer Res. 69(9):4010-7, 2009 [PMCID: PMC2716664]
127. Pérez-Martínez A, Leung W, Muñoz E, Iyengar R, Ramírez M, Vicario JL, Lassaletta A, Sevilla J, González-Vicent M, Madero L, Díaz-Pérez MA.
     KIR-HLA receptor-ligand mismatch associated with a graft-versus-tumor effect in haploidentical stem cell transplantation for pediatric metastatic solid tumors. Pediatr Blood Cancer. 53(1):120-124, 2009
128. Kasow KA, Krueger J, Srivastava DK, Li C, Barfield R, Leung W, Horwitz EM, Madden R, Woodard P, Hussain I, McCarville MB, Handgretinger R, Hale GA.
     Clinical utility of computed tomography screening of chest, abdomen, and sinuses before hematopoietic stem cell transplantation: the St. Jude experience. Biol Blood Marrow Transplant. 15(4):490-5, 2009 [PMCID: PMC2679960]
129. Call SK, Kasow KA, Barfield R, Madden R, Leung W, Horwitz E, Woodard P, Panetta JC, Baker S, Handgretinger R, Rodman J, Hale GA.
     Total and active rabbit antithymocyte globulin pharmacokinetics in pediatric patients undergoing unrelated donor bone marrow transplantation. Biol Blood Marrow Transplant. 15(2):274-8, 2009
130. Phipps S, Rai SN, Leung W, Lensing S, Dunavant M.
     Cognitive and academic consequences of stem-cell transplantation in children. J Clin Oncol. 26(12):2027-2033, 2008.
131. Leung W, Handgretinger R, Iyengar R, Turner V, Holladay MS, Hale GA.
     Inhibitory KIR-HLA receptor-ligand mismatch in autologous haematopoietic stem cell transplantation for solid tumour and lymphoma. Br J Cancer 97(4):539-542, 2007 [PMCID: PMC2360345]
132. Leung W, Ahn H, Rose SR, Phipps S, Smith T, Gan K, O'connor M, Hale GA, Kasow KA, Barfield RC, Madden RM, Pui CH.
     A Prospective Cohort Study of Late Sequelae of Pediatric Allogeneic Hematopoietic Stem Cell Transplantation. Medicine 86(4):215-224, 2007
133. Madden RM, Pui CH, Hughes WT, Flynn PM, Leung W.
     Prophylaxis of Pneumocystis carinii pneumonia with atovaquone in children with leukemia. Cancer 109(8):1654-1658, 2007
134. Kasow KA, King E, Rochester R, Tong X, Srivastava DK, Horwitz EM, Leung W, Woodard P, Handgretinger R, Hale GA.
     Diagnostic yield of bronchoalveolar lavage is low in allogeneic hematopoietic stem cell recipients receiving immunosuppressive therapy or with acute graft-versus-host disease: the St. Jude experience, 1990-2002. Biol Blood Marrow Transplant 13(7):831-7, 2007
135. Otto M, Chen X, Martin WJ, Leung W, Knowles J, Holladay M, Houston J, Handgretinger R, Barfield RC.
     Selection of stem cells by using antibodies that target different CD34 epitopes yields different patterns of T-cell differentiation. Stem Cells. 25:537-42, 2007
136. Kasow KA, Leung W, Horwitz EM, Woodard P, Handgretinger R, Hale GA.
     EBV lymphoproliferative disease of host origin after haploidentical stem cell transplantation. Pediatr Blood Cancer. 49:869-72, 2007
137. Triplett B, Handgretinger R, Pui CH, Leung W.
     KIR-incompatible hematopoietic-cell transplantation for poor prognosis infant acute lymphoblastic leukemia.Blood. 107(3):1238-9, 2006.
138. Inaba H, Handgretinger R, Furman W, Hale G, Leung W.
     Allogeneic graft-versus-hepatoblastoma effect. Pediatr Blood Cancer. 46(4):501-5, 2006.
139. Chen X, Hale GA, Barfield R, Benaim E, Leung W, Knowles J, Horwitz EM, Woodard P, Kasow K, Yusuf U, Behm FG, Hayden RT, Shurtleff SA, Turner V, Srivastava DK, Handgretinger R.
     Rapid immune reconstitution after a reduced-intensity conditioning regimen and a CD3-depleted haploidentical stem cell graft for paediatric refractory haematological malignancies. Br J Haematol. 135(4):524-32, 2006
140. Inaba H, Hale G, Leung W, Woodard P, Burnette K, Handgretinger R, Barfield R.
     Diagnostic Challenge in Recurrent Skin Rash After Autologous Bone Marrow Transplantation. J Pediatr Hematol Oncol. 28(8):525-528, 2006
141. Yusuf U, Hale GA, Carr J, Gu Z, Benaim E, Woodard P, Kasow KA, Horwitz EM, Leung W, Srivastava DK, Handgretinger R, Hayden RT.
     Cidofovir for the treatment of adenoviral infection in pediatric hematopoietic stem cell transplant patients. Transplantation 81(10):1398-404, 2006
142. Woodard P, Barfield R, Hale G, Horwitz E, Leung W, Ribeiro R, Rubnitz J, Srivistava DK, Tong X, Yusuf U, Raimondi S, Pui CH, Handgretinger R, Cunningham JM.
     Outcome of hematopoietic stem cell transplantation for pediatric patients with therapy-related acute myeloid leukemia or myelodysplastic syndrome. Pediatr Blood Cancer. 47(7):931-5, 2006
143. Leung W, Iyengar R, Triplett B, Turner V, Behm FG, Holladay MS, Houston J, Handgretinger R.
     Comparison of Killer Ig-Like Receptor Genotyping and Phenotyping for Selection of Allogeneic Blood Stem Cell Donors. J Immunol. 174(10):6540-6545, 2005
144. Leung W, Iyengar R, Leimig T, Holladay MS, Houston J, Handgretinger R.
     Phenotype and function of human natural killer cells purified by using a clinical-scale immunomagnetic method. Cancer Immunol Immunother. 54(4):389-94, 2005.
145. Otto M, Barfield RC, Martin WJ, Iyengar R, Leung W, Leimig T, Chaleff S, Gillies SD, Handgretinger R.
     Combination immunotherapy with clinical-scale enriched human gammadelta T cells, hu14.18 antibody, and the immunocytokine Fc-IL7 in disseminated neuroblastoma. Clin Cancer Res. 11(23):8486-91, 2005
146. Otto M, Barfield RC, Iyengar R, Gatewood J, Muller I, Holladay MS, Houston J, Leung W, Handgretinger R.
     Human gammadelta T Cells From G-CSF-Mobilized Donors Retain Strong Tumoricidal Activity and Produce Immunomodulatory Cytokines After Clinical-Scale Isolation. J Immunother. 28(1):73-78, 2005.
147. Chen X, Barfield R, Benaim E, Leung W, Knowles J, Lawrence D, Otto M, Shurtleff SA, Neale GA, Behm FG, Turner V, Handgretinger R.
     Prediction of T-cell reconstitution by assessment of T-cell receptor excision circle before allogeneic hematopoietic stem cell transplantation in pediatric patients. Blood. 105(2):886-93, 2005
148. Leung W, Iyengar R, Turner V, Lang P, Bader P, Conn P, Niethamer D, Handgretinger R.
     Determinants of antileukemia effects of allogeneic NK cells. J Immunol. 172(1):644-650, 2004.
149. Khan RB, Krasin MJ, Kasow K, Leung W.
     Cyclooxygenase-2 inhibition to treat radiation-induced brain necrosis and edema. J Pediatr Hematol Oncol.  26(4):253-5, 2004
150. Woodard P, Helton K, McDaniel H, Khan R, Thompson S, Hale G, Benaim E, Kasow K, Leung W, Horwitz E, Srivastava DK, Tong X, Yusuf U, Cunningham J, Handgretinger R.
     Encephalopathy in pediatric patients after allogeneic hematopoietic stem cell transplantation is associated with a poor prognosis. Bone Marrow Transplant. 33(11):1151-7, 2004.
151. Woodard P, Cunningham JM, Benaim E, Chen X, Hale G, Horwitz E, Houston J, Kasow K, Leung W, Wang W, Yusuf U, Handgretinger R.
     Effective donor lymphohematopoietic reconstitution after haploidentical CD34+-selected hematopoietic stem cell transplantation in children with refractory severe aplastic anemia. Bone Marrow Transplant 33(4):411-8, 2004.
152. Iyengar R, Handgretinger R, Babarin A, Leimig T, Otto M, Geiger T, Holladay M, Houston J, Leung W.
     Purification of human natural killer cells using a clinical-scale immunomagnetic method. Cytotherapy 5(6):479-84, 2003. 
153. Kasow KA, Handgretinger R, Krasin MJ, Pappo AS, Leung W.
     Possible allogeneic graft-versus-tumor effect in childhood melanoma. J Pediatr Hematol Oncol. 25(12):982-986, 2003  
154. Lowe EJ, Turner V, Handgretinger R, Horwitz EM, Benaim E, Hale GA, Woodard P, Leung W.
     T-cell alloreactivity dominates natural killer cell alloreactivity in minimally T-cell-depleted HLA-non-identical paediatric bone marrow transplantation. Br J Haematol 123(2):323-6, 2003 
155. Pui CH, Cheng C, Leung W, Rai SN, Rivera GK, Sandlund JT, Relling MV, Kun LE, Evans WE, Hudson MM.
     Extended follow-up of long-term survivors of childhood acute lymphoblastic leukemia. N Engl J Med. 349(7):640-9, 2003
156. Hale GA, Rochester RJ, Heslop HE, Krance RA, Gingrich JR, Benaim E, Horwitz EM, Cunningham JM, Tong X, Srivastava DK, Leung W, Woodard P, Bowman LC, Handgretinger R.
     Hemorrhagic cystitis after allogeneic bone marrow transplantation in children: clinical characteristics and outcome. Biol Blood Marrow Transplant. 9(11):698-705, 2003. 
157. Woodard P, Tong X, Richardson S, Srivastava DK, Horwitz EM, Benaim E, Geiger T, Hale G, Leung W, Turner V, Yusuf U, Cunningham J, Handgretinger R.
     Etiology and outcome of graft failure in pediatric hematopoietic stem cell transplant recipients. J Pediatr Hematol Oncol 25(12):955-9, 2003.
158. Handgretinger R, Leung W, Ihm K, Lang P, Klingebiel T, Niethammer D.
     Tumour cell contamination of autologous stem cells grafts in high-risk neuroblastoma: the good news? Br J Cancer 88:1874-7, 2003.
159. Hale GA, Bowman LC, Woodard JP, Cunningham J, Benaim E, Horwitz E, Heslop HE, Krance RA, Leung W, Shearer PD, Handgretinger R.
     Allogeneic bone marrow transplantation for children with histiocytic disorders: use of TBI and omission of etoposide in the conditioning regimen. Bone Marrow Transplant  31:981-6, 2003
160. Leung W, Rose SR, Zhou Y, Hancock ML, Burstein S, Schriock EA, Lustig R, Danish RK, Evans WE, Hudson MM, Pui CH.
     Outcomes of growth hormone replacement therapy in survivors of childhood acute lymphoblastic leukemia. J Clin Oncol 20(13):2959-2964, 2002
161. Leung W. 
     Update on late effects of treatment in survivors of childhood acute myeloid leukemia.  J Clin Oncol Classic Papers & Current Comments 7(2):312-319, 2002
162. Leung W, Sandlund JT, Hudson MM, Zhou Y, Hancock ML, Zhu Y, Ribeiro RC, Rubnitz JE, Kun LE, Razzouk B, Evans WE, Pui CH.
     Second malignancy after treatment of childhood non-Hodgkin lymphoma. Cancer 92(7):1959-1966, 2001
163. Leung W, Ribeiro RC, Hudson M, Tong X, Srivastava DK, Rubnitz JE, Sandlund JT, Razzouk BI, Evans WE, Pui CH. 
     econd malignancy after treatment of childhood acute myeloid leukemia.  Leukemia 15:41-45, 2001.
164. Leung W, Pitts N, Burnette K, Cunningham JM, Horwitz EM, Benaim E, Hale GA, Woodard P, Pui CH, Bowman LC. 
     Allogeneic bone marrow transplantation for infants with acute leukemia or myelodysplastic syndrome.  Bone Marrow Transplant 27:717-722, 2001
165. Leung W, Turner V, Richardson S, Horwitz EM, Benaim E, Hale GA, Woodard P, Bowman LC. 
     Effect of HLA class I or class II incompatibility in pediatric marrow transplantation from unrelated and related donors.  Hum Immunol 62:399-407, 2001.
166. Hale GA, Tong X, Benaim E, Cunningham JM, Heslop HE, Horwitz EM, Leung W, Rochester RJ, Shearer PD, Srivastava DK, Woodard JP, Bowman LC. 
     Allogeneic bone marrow transplantation in children failing prior autologous bone marrow transplantation.  Bone Marrow Transplant 27:155-162, 2001.
167. Gao Z, Fackler MJ, Leung W, Lumkul R, Ramirez M, Theobald N, Malech HL, Civin CI.
     Human CD34(+) cell preparations contain over 100-fold greater NOD/SCID mouse engrafting capacity than do CD34(-) cell preparations. Exp Hematol  29(7):910-21, 2001
168. Leung W, Hudson MM, Strickland DK, Phipps S, Srivastava DK, Ribeiro RC, Rubnitz JE, Sandlund JT, Kun LE, Bowman LC, Razzouk BI, Mathew P, Shearer P, Evans WE, Pui CH. 
     Late effects of treatment in survivors of childhood acute myeloid leukemia.  J Clin Oncol 18:3273-3279, 2000.
169. Leung W, Hudson M, Zhu Y, Rivera GK, Ribeiro RC, Sandlund JT, Bowman LC, Evans WE, Kun L, Pui CH. 
     Late effects in survivors of infant leukemia.  Leukemia 14:1185-1190, 2000.
170. Leung W, Ramirez M, Civin CI. 
     Quantity and quality of engrafting cells in cord blood and autologous mobilized peripheral blood.  Biol Blood Marrow Transplant 5(2):69-76, 1999.
171. Leung W, Ramirez M, Mukherjee G, Perlman EJ, Civin CI. 
     Comparisons of alloreactive potential of clinical hematopoietic grafts.  Transplantation 68:628-635, 1999.
172. Leung W, Columbani P, Lau H, Schwarz K, Friedman A. 
     Long term complete remission and immune tolerance after intensive chemotherapy for lymphoproliferative disorder complicating liver transplant.  Transplantation 67(11):1487-1489, 1999.
173. Leung W, Blakemore K, Jones RJ, Moser HW, Griffin CA, Mukherjee G, Civin CI. 
     A human /murine chimera model for in utero human hematopoietic stem cell transplantation.  Biol Blood Marrow Transplant 5(1):1-7, 1999.
174. Novelli EM, Cheng L, Yang Y, Leung W, Ramirez M, Tanavde V, Enger C, Civin CI.
     Ex vivo culture of cord blood CD34+ cells expands progenitor cell numbers, preserves engraftment capacity in NOD/SCID mice, and enhances retroviral transduction efficiency.  Hum Gene Ther 10:2927-2940, 1999.
175. Novelli EM, Ramirez M, Leung W, Civin CI.
     Human hematopoietic stem/progenitor cells generate CD5+ B lymphoid cells in NOD/SCID mice.  Stem Cells 17:242-252, 1999.
176. Leung W, Ramirez M, Novelli EM, Civin CI. 
     In vivo engraftment potential of clinical hematopoietic grafts.  J Invest Med 46(6):303-311, 1998.
177. Leung W, Chen AR, Klann RC, Moss TJ, Davis JM, Noga SJ, Cohen KJ, Friedman AD, Small D, Schwartz CL, Borowitz MJ, Wharam MD, Paidas CN, Long CA, Karandish S, McMannis JD, Kastan MB, Civin CI. 
     Frequent detection of tumor cells in hematopoietic grafts in neuroblastoma and Ewing’s sarcoma.  Bone Marrow Transplant 22(10):971-979, 1998.
178. Leung W.
     Infusions of Allogeneic Natural Killer Cells as Cancer Therapy. Clin Cancer Res. 20(13):3390-3400, 2014
179. Campana D, Leung W.
     Clinical significance of minimal residual disease in patients with acute leukaemia undergoing haematopoietic stem cell transplantation. Br J Haematol. 162(2):147-61, 2013
180. Shook DR, Leung W.
     Natural killer cell therapy for cancer: delivering on a promise. Transfusion. 53(2):245-8, 2013.
181. Leung W.
     Use of NK cell activity in cure by transplant. Br J Haematol. 155(1):14-29, 2011
182. Leung W, Pulsipher M.
     Hematopoietic stem cell and NK cell transplantation. In Childhood Leukemia, ed. Pui CH. Cambridge University Press, 2011.
183. Leung W.
     The role of natural killer cells in transplant and the non-tranplant scenario. American Society of Oncology (ASCO) Educational Book, 2010.
184. Leung W.
     Immunotherapy in acute leukemia. Semin Hematol. 46(1):89-99, 2009 [PMCID: PMC2839547]
185. Leung W, Rose SR, Merchant TE.
     Neuroendocrine complications of cancer therapy. In Survivors of Childhood and Adolescent Cancer, ed. Schwartz CL, pp 51-80. Springer-Verlag GmBH & Co., 2005.
186. Leung W, Chen AR, Civin CI. 
     Use of purified stem and progenitor cells for transplantation.  In Clinical bone marrow and blood stem cell transplantation, ed. Atkinson K, pp 1191- 1204. Cambridge: Cambridge University Press, 2000.
187. Leung W, Civin CI.
     CD34+ cell selection technologies. In Clinical bone marrow and blood stem cell transplantation, ed. Atkinson K, pp 1205- 1204-1210. Cambridge: Cambridge University Press, 2000.
188. Leung W, Handgretinger R, Turner V, Hale GA.
     Missing ligand model in autologous stem cell transplantation. Br J Cancer. 26;98(4):854-855, 2008
189. Leung W.
     Allogeneic BMT for infantile acute leukemia: what is the optimal conditioning regimen? Bone Marrow Transplant 29(7):630-631, 2002

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