Selected Publications with Higher Degree Students

  1. L. Peng, E.H.W. Leung, J. So, P.H.S. Mak, C.L. Lee, H. Tan, K.F. Lee and S.Y. Chan (2020) TSPYL1 regulates steroidogenic gene expression and male fertility in mice. F&S Science, doi: https://doi.org/10.1016/j.xfss.2020.08.001.
  2. C.H. Chong, Q. Li, P.H.S. Mak, C.C.P. Ng, E.H.W. Leung, V.H. Tan, A.K.W. Chan, G. McAlonan, S.Y. Chan (2019) Lrrc7 mutant mice model developmental emotional dysregulation that can be alleviated by mGluR5 allosteric modulation. Translational Psychiatry, 9,244.
  3. H. Liu, L. Peng, J. So, K.H. Tsang, C.H. Chong, P.H.S. Mak, K.M. Chan and S.Y. Chan (2018) TSPYL2 regulates the expression of EZH2 target genes in neurons. Molecular Neurobiology doi: 10.1007/s12035-018-1238-y.
  4. Q. Li, S.Y. Chan, K.K. Wong, R. Wei, Y.O. Leung, A.Y. Ding, T.C. Hui, C. Cheung, S.E. Chua, P.C. Sham, E.X. Wu and G.M. McAlonan. (2016) TSPYL2 loss-of-function causes neurodevelopmental brain and behaviour abnormalities in mice. Behavior Genetics 46(4), 529-37.
  5. K.H. Tsang, S.K. Lai, Q. Li, W.H. Yung, H. Liu, H.S. Mak, C.P. Ng, G. McAlonan, Y.S. Chan and S.Y. Chan (2014) The nucleosome assembly protein TSPYL2 regulates the expression of NMDA receptor subunits GluN2A and GluN2B. Sci. Rep., 13(4), 3654.
  6. K. P. Tao, S. W. Fong, Z. Lu, Y. P. Ching , K. W. Chan, S.Y. Chan (2011) TSPYL2 is important for G1 checkpoint maintenance upon DNA damage. PLoS One, 6(6), e21602.
  7. Y. Liang, P. H. Chiu, K.Y. Yip and S.Y.Chan (2011) Subcellular localization of SUN2 is regulated by lamin A and rab5. PLoS One, 6(5), e20507.
  8. R.H.K. Lee, W.L. Wong, C.H. Chan and S.Y. Chan (2006) Differential effects of glial cell line-derived neurotrophic factor and neurturin in RET/GFR�\ expressing cells. J. Neurosci. Res., 83, 80-90.
  9. S.Y. Chan, A.K.W. Chan, B.P.K. Cheung, Y. Liang, M. P. Leung (2003) Identification of genes expressed during myocardial development by Suppression Subtractive Hybridisation. Chinese Medical Journal, 116(9), 1329-1332.
  10. K.K.L. Mak and S.Y. Chan (2003) Epidermal growth factor as a biologic switch in the hair cycle.J. Biol. Chem., 278, 26120-26126.
  11. D.C.W. Lee, K.W. Chan, S.Y. Chan (2002) RET receptor tyrosine kinase isoforms in kidney function and disease. Oncogene, 21, 5582-5592.
  12. R.W.C. Wong, M. Dong, K.K.L. Mak, S.Y. Chan (2001) Prospects of EGF transgenic mice researches,Acta Biochim. Biophy. Sin. 33(5), 473-476.
  13. R.W.C. Wong, R.W.P. Kwan, P.H.S. Mak, K.K.L. Mak, M.H. Sham and S.Y. Chan (2000) Overexpression of epidermal growth factor induced hypospermatogenesis in transgenic mice. J. Biol. Chem., 275(24), 18297-18301.
  14. S.Y. Chan and R.W.C. Wong (2000) Expression of epidermal growth factor in transgenic mice causes growth retardation. J. Biol. Chem., 275(49), 38693-38698.
  15. W.K. Ip, Y.L. Lau, S.Y. Chan, C.C. Mok, D. Chan, K.K. Tong and C.S. Lau (2000) Mannose-binding lectin and rheumatoid arthritis in Southern Chinese,Arthritis Rheum., 43(8), 1679-1687.
  16. R.W.C. Wong, M.H. Sham, Y.L. Lau and S.Y. Chan (2000) An efficient method of generating transgenic mice by pronuclear microinjection, Mol. Biotechnol, 15(2), 155-159.
  17. R.W.C. Wong and S.Y. Chan (2000) Semi-quantitative immunoblots of membrane protein-epidermal growth factor,Mol. Biotechnol., 15(1), 65-67.
  18. K.L. Yip, S.Y. Chan and Y.L. Lau, (2000) Bruton's tyrosine kinase (btk) gene mutation in 9 Chinese families with X-linked agammaglobulinemia,Hum. Mutat, 15(4), 386 (Mutation in Brief #312 on line).
  19. S.Y.Chan, Y.F. Hui and Y.L. Lau (1999) A 11-bp deletion in exon 10 (c1295del11)of WASP responsible for Wiskott-Aldrich Syndrome, Human Mutation Mutation and Polymorphism report #56 on line (c1295del11).
  20. R.W.P. Kwan, R.W.C. Wong, S.Y. Chan (1999) Expression of full length or truncated epidermal growth factor precursor transforms NIH3T3 fibroblasts,Int. J. Oncology, 15, 281-284.
  21. W.K. Ip, S.Y. Chan, C.S. Lau and Y.L. Lau (1998) Association of systemic lupus erythematosus with promoter polymorphisms of the mannose- binding lectin gene, Arthritis Rheum., 41(9), 1663-1667.
  22. S.Y. Chan and D.C.W. Lee (1998) Sex difference in immunostaining of RET in the adult mouse kidney,Oncogene, 17, 661-666.
  23. D.C.W. Lee, K.W. Chan and S.Y. Chan (1998) Expression of TGF�\ and EGF in adult polycystic kidney disease,J. Urology, 159, 291-296.
  24. Y.F. Hui, S.Y. Chan and Y.L. Lau (1996) Identification of mutations in seven Chinese patients with X-linked chronic granulomatous disease, Blood, 88(10), 4021-4028.

 
Back