Dr. Chan Hoi Shan Sophelia (陳凱珊)

MBBS(HK), MRCP(UK), MMedSc(HKU)(Core:Genetic Counseling), FHKAM(Paed), FHKCPaed (Paediatric Neurology)

 

Clinical Assistant Professor

Honorary Associate Consultant

Division of Neurology, Developmental Paediatrics & Neurohabilitation

Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine,

The University of Hong Kong

 

Specialty

Paediatric Neurology

Developmental Behavioural Paediatrics

 

Awards

香港 瑪麗醫院 大口環根德公爵夫人兒童醫院 兒童神經肌肉疾病診療服務
Queen Mary Hospital and the Duchess of Kent Children's Hospital, Hong Kong -- Paediatric Neuromuscular Diagnostic and Management Program

 

Contact

Tel:

Fax:

Email:

Office:

(852) 22554090
(852) 22554089
sophehs@hku.hk
Department of Paediatrics & Adolescent Medicine
Room 115, 1/F, New Clinical Building
102 Pokfulam Road, Queen Mary Hospital, Hong Kong

 

Research

 

Paediatric Neurology, Developmental Behavioural Paediatrics and Paediatric Neurorehabilitation

 

Research work focus

 

Funded projects

 

Donation funds from the Society for the Relieve of Disabled Children in Duchess of Kent Children's Hospital

 

Selected publications

 

  1. Baertling F, Sánchez-Caballero L, van den Brand MA, Fung CW, Chan SHS, Wong VC, Hellebrekers DME, de Coo IFM, Smeitink JA, Rodenburg RJ, Nijtmans LG. NDUFA9 point mutations cause a variable mitochondrial complex I assembly defect. Clin Genet. 2017 Jul 3. doi: 10.1111/cge.13089. [Epub ahead of print]
  2. Donkervoort S, Chan SHS, Hayes LH, Bradley N, Nguyen D, Leach ME, Mohassel P, Hu Y, Thangarajh M, Bharucha-Goebel D, Kan A, Ho RSL, Reyes CA, Nance J, Moore SA, Foley AR, Bönnemann CG. Cytoplasmic body pathology in severe ACTA1-related myopathy in the absence of typical nemaline rods. Donkervoort S, Chan SHS, Hayes LH, Bradley N, Nguyen D, Leach ME, Mohassel P, Hu Y, Thangarajh M, Bharucha-Goebel D, Kan A, Ho RSL, Reyes CA, Nance J, Moore SA, Foley AR, Bönnemann CG. Neuromuscul Disord. 2017 Jun;27(6):531-536. doi: 10.1016/j.nmd.2017.02.012. Epub 2017 Mar 2.
  3. Sophelia HS Chan, Ivan FM Lo, Ronnie SL Ho, KS Lun. X-linked dilated cardiomyopathy with mutation in the 5’splice site intron 1 of dystrophin gene with utrophin upregulation. J Pediatr Neurol. 2017 doi.org/ 10.1055/s-0037-1603997 [ahead of print]
  4. Iris Chung, Brian Chung ,Sophelia HS Chan. Is it or is it not Vaccine-associated paralytic poliomyelitis: A case report of acute flaccid paralysis after oral polio vaccine booster dose. Hong Kong Journal of Paediatrics ( new series) 2016;21:105-108
  5. CL Bladen, D Salgado, S Monges, ME. Foncuberta, K Kekou, K Kosma, H Dawkin, L Lamont, A Roy, T Chamova, V Guergueltcheva, Sophelia Chan, L Korngut, C Campbell, Yi Dai, et al. The TREAT-NMD DMD Global database. Analysis of more than 700 Duchenne Muscular Dystrophy mutations. Human Mutation 2015;36(4):395-402.
  6. Sophelia HS Chan, Ivan FM Lo, Sharon Cherk, WW Cheng, Eva LW Fung, WL Yeung, M Ngan, WC Lee, Karen L Kwong, SN Wong, CK Ma, Tai SM, SF Ng, SP Wu, VCN Wong. Characteristic of patients with Duchenne Muscular Dystrophy and Becker Muscular Dystrophy in Hong Kong. Child Neurology Open 2015: Apr - June 2015: 1-8 DOI: 10.1177/2329048X15585345
  7. Sophelia HS Chan, A Reghan Foley, Rahul Phadke, Ann Agnes Mathew, Matthew Pitt, Caroline Sewry, Francesco Muntoni. Limb girdle muscular dystrophy due to LAMA2 mutations: diagnostic difficulties due to associated peripheral neuropathy. Neuromuscular Disorder 2014:24(8);677-683
  8. Sophelia HS Chan, Dickson SF Tsang, Virginia CN Wong, Godfrey CF Chan. Spinal primitive neuroectodermal tumour mimicking as chronic inflammatory demyelinating polyneuropathy – a case report and review of literatures. J Child Neurology 2015;30(2)::254-8.
  9. Sophelia H.S. Chan , Virginia C.N. Wong , Andrew G. Engel. Neuromuscular Junction Acetylcholinesterase Deficiency Responsive to Albuterol. Pediatric Neurology 2012: 47(2):134-140  
  10. Sophelia HS Chan, Virginia CN Wong, CW Fung, Rusell C Dale, Angela Vincent. Anti-NMDAR encephalitis with atypical MRI brain changes. Pediatric Neurology 2010: 43: 4: 274-278.
  11. SHS Chan, KY Yam, BPHL Yiu, CYC Poon , NNC Chan, HM Cheung, MMF Wu, WK Chak. Selective Dorsal Rhizotomy in Hong Kong: A multidimensional outcome measures. Pediatric Neurology 2008; 39;22-32
  12. WKL Yam, HSS Chan, KW Tsui, BPH Yiu, SSL Fong, CYK Cheng, CW Chan. Prevalence study of cerebral palsy in Hong Kong. Working Group on Cerebral Palsy, Hong Kong Society of Child Neurology and Developmental Paediatrics. Hong Kong Medical Journal 2006;12(3):180-184.
  13. HSS Chan, PHB Lau, KH Fong, D Poon, CCC Lam. Neuroimpairment, activity limitation and participation restriction among children with cerebral palsy in Hong Kong. Hong Kong Medical Journal 2005;11(5):342-350

 

Book Chapters

 

  1. Cerebral Palsy
    Sophelia HS Chan
    , Cherri CY Ho
    Chapter 4. In Rose HL Mak, Catherine CC Lam, Cherri CY Ho, May MY Wong (Ed). A primer in Common Developmental Disabilities, Experience at Child Assessment Service, Hong Kong SAR (2006). ISBN 9628868179, 9789628868179
  2. Developmental Coordination Disorder
    Sophelia HS Chan
    Chapter 5. In Rose HL Mak, Catherine CC Lam, Cherri CY Ho, May MY Wong (Ed). A primer in Common Developmental Disabilities, Experience at Child Assessment Service, Hong Kong SAR (2006). ISBN 9628868179, 9789628868179