Dr Alan Kwok-shing Chiang (蔣國誠)

BSc(St. Andrews), MBChB(Manc), PhD(HK), FHKAM, FRCPCH, FRCP(Edin, Glasg, Lond)

 

Clinical Associate Professor
Department of
Paediatrics and Adolescent Medicine, LKS Faculty of Medicine,
The University of Hong Kong

 

Specialty

 

 

Awards

Sir Edward Youde Memorial Fellowship 1994-1996

Croucher Foundation Scholarship, 1994-1997

Young Investigators' Award, Hong Kong International Cancer Congress, 1995

Best free paper presentation, HKSI/FIMSA Advanced Course and Conference: From Basic to Applied Immunology, 1998 Dr. KP Stephen Chang Gold Medal, 1998

Li Ka Shing Prize, 1997-1999 for best PhD thesis

 

Contact

Email:

Tel:

Fax:
Office:

chiangak@hku.hk
(852) 22554091
(852) 28551523
Department of Paediatrics & Adolescent Medicine
Room 115, 1/F, New Clinical Building
102 Pokfulam Road, Queen Mary Hospital, Hong Kong

 

ebv-laboratory

Chiang Lab - EBV Research

· Assistant Research Officer

Research

 

Research areas

 

I am a clinician-scientist practising in the field of paediatric haematology and oncology. My research interest in Epstein-Barr virus (EBV) biology dated back to my PhD studies at the Department of Pathology of The University of Hong Kong where I was delineating the pathogenic role of EBV in an intriguing EBV-associated malignancy affecting the Chinese population, nasal NK/T cell lymphoma (NL). My work on defining the tumour cell characteristics at the DNA, RNA and protein level and the uniform presence of EBV in the tumour cells had contributed to the WHO classification of this malignancy as a distinct clinicopathologic entity and the prototypic NK cell lymphoma. Studies on EBV gene expression and immune evasion of this tumour revealed that EBV latent genes are downregulated into a latency II pattern and the HLA class I pathway is largely maintained in NL but tumour resistance to cytotoxic T cells might be partly mediated by expression of immunomodulatory cytokines such as interleukin 10 in the tumour microenvironment. The research work was extended to the analysis of EBV carriage in normal healthy individuals, which revealed that coinfection of multiple strains of EBV was unexpectedly prevalent whilst particular viral strains characterized by a 30-bp deletion in the LMP gene might be preferentially selected in NL. The Chiang lab focuses on the understanding of host-virus interactions in primary and persistent EBV infection and on the elucidation of pathogenic mechanisms of EBV in lymphoid and epithelial cancers. Research programs include: (i) Role of adaptive and innate immune responses in the control of EBV: longitudinal study of viral loads, humoral and CD8+ T cell responses in primary EBV infection in Chinese children and development of novel assays in polychromatic flow cytometry to dissect such immune responses; (ii) Sequence analysis of EBV strains in EBV infection subjects and EBV-positive malignancies: development of novel assays in characterizing EBV strains to study distribution and inter-change of EBV strains among different body compartments and to discover pathogenic viral strains in malignancies; (iii) Novel therapeutic strategies for EBV-positive lymphoid and epithelial cancers: discovering action of different compounds in inducing lytic cycle of EBV in cancer cells and dissecting mechanistic pathways of viral lytic induction.

  

Research Grants

 

l Prospective study of virologic and immunologic parameters of primary Epstein-Barr virus infection in Chinese children. RGC-CERG, 2003
l Prospective study of Epstein-Barr virus (EBV) strains in primary EBV infection. CRCG, 2004
l Biology of Epstein-Barr virus in health and in disease. Private donation, 2005
l Longitudinal study of Epstein-Barr virus specific antibody responses in childhood infectious mononucleosis. CRCG, 2005
l Longitudinal study of phenotypic changes and functionality of Epstein-Barr Virus (EBV)-specific CD8+ T cell responses in symptomatic and asymptomatic EBV infection. RGC-CERG 2007
l Activation of Epstein-Barr virus (EBV) in EBV-associated malignancy. CRCG, 2007
l Sequence analysis of Epstein-Barr virus strains in nasopharyngeal carcinoma. RGC-GRF 2008
l Mechanistic studies of Epstein-Barr virus (EBV) lytic cycle induction in nasopharyngeal carcinoma. Nasopharyngeal Carcinoma Area of Excellence Grant, 2010-2012

 

Research Publications

 

A. (Journal papers/Articles; International)

  1. Hui KF, Cheung AK, Choi CK, Yeung PL, Middeldorp JM, Lung ML, Tsao SW, Chiang AKS: Inhibition of clasee I histone deacetylases by romidepsin potently induces Epstein-Barr virus lytic cycle and mediates enhanced cell death with ganciclovir. Int J Cancer 2015 Jul 23. Doi: 10.1002/ijc.29698 (Contribution: Major)
  2. Cheuk DKL, Chiang AKS, Ha SY, Chan GC: Interventions for prophylaxis of hepatic veno-occlusive disease in people undergoing haematopoietic stem cell transplantation. Cochrane Database Syst Rev 5: CD009311, 2015 (Contribution: Major)
  3. Kwok H, Chan KW, Chan KH, Chiang AKS: Distribution, persistence and interchange of Epstein-Barr virus strains among PBMC, plasma and saliva of primary infection subjects. PLoS One 10: e0120710, 2015 (Contribution: Major)
  4. Chu YW, Cheuk DK, Chung BH, Bowers NL, Ha SY, Chiang AKS, Chan GC: A patient with mosaic neurofibormatosis type 2 presenting with early onset meningioma. BMJ Case Rep 2014 Nov 18. Doi; 10.1136/bcr-2014-203919 (Contribution: Minor)
  5. Hau PM, Deng W, Jia L, Yang J, Tsurumi T, Chiang AKS, Huen MS, Tsao SW: Role of ATM in the formation of replication compartment during lytic replication of EBV in nasopharyngeal epithelial cells. J Virol 89: 652-668, 2015 (Contribution: Minor)
  6. Iu LP, Yeung JC, Loong F, Chiang AKS: Successful treatment of intraocular post-transplant lymphoproliferative disorder with intravenous rituximab. Pediatr Blood Cancer 62: 169-172, 2015 (Contribution: Major)
  7. So CC, Chiang AKS, Kan A, Lee V, NgE: Beta thalassaemia intermedia due to silent alpha globin gene quadriplication in an infant. Pathology 46: 570-2, 2014 (Contribution: Major)
  8. Hui KF, Leung YY, Yeung PL, Middeldorp JM, Chiang AKS: Combination of SAHA and bortezomib up-regulates CDKN2A and CDKN1A and induces apoptosis of Epstein-Barr virus-positive Wp-restricted Burkitt lymphoma and lymphoblastoid cell lines. Br J Haematol 167: 639-650, 2014 (Contribution: Major)
  9. Cheuk DKL, Chiang AKS, Chan GCF, Ha SY: Urate oxidase for the prevention and treatment of tumour lysis syndrome in children with cancer. Cochrane Database Syst Rev 8: CD006945, 2014 (Contribution: Major)
  10. Kwok H, Wu CW, Palser AL, Kellam P, Sham PC, Kwong DL, Chiang AKS: Genomic diversity of Epstein-Barr virus genomes isolated from primary nasopharyngeal carcinoma biopsy samples. J Virol 88: 10662-10672, 2014 (Contribution: Major)
  11. Dee CM, Cheuk DKL, Ha SY, Chiang AKS, Chan GCF: Incidence of deferasirox-associated renal tubular dysfunction in children and young adults with beta-thalassaemia. Br J Haematol 167: 434-436, 2014 (Contribution: Minor)
  12. Hui KF, Chiang AKS: Combination of proteasome and class I HDAC inhibitors induces apoptosis of NPC cells through an HDAC6-independent ER stress-induced mechanism. Int J Cancer 135: 2950-2961, 2014  (Contribution: Major)
  13. Fule Robles JD, Cheuk DKL, Ha SY, Chiang AKS, Chan GCF: Human herpesvirus types 6 and 7 infection in pediatric hematopoietic stem cell transplant recipients. Ann Transplant 19: 269-276, 2014  (Contribution: Minor)
  14. Chiang AKS, Mak NK, Ng WT: Translational research in nasopharyngeal carcinoma. Oral Oncol 50: 345-352, 2014 (Contribution: Major)
  15. Chen J, Lee V, Luo JC, Chiang AKS, Hongeng S, Tan PL, Tan AM, Sanpakit K, Li CF, Lee AC, Chua HC, Okamoto Y: Allogeneic stem cell transplantation for children with acquired severe aplastic anaemia: a retrospective study by the Viva-Asia Blood and Marrow Transplantation Group. Br J Haematol 162: 383-391, 2013 (Contribution: Major)
  16. Attarbaschi A, Beishuizen A, Mann G, Rosolen A, Mori T, Uyttebroeck A, Niggli F, Csoka M, Krenova Z, Mellgren K, Kabickova E, Chiang AKS, Reiter A, Williams D, Burkhardt B; European Intergroup for Childhood Non-Hodgkin Lymphoma (EICNHL) and the International Berlin-Frankfurt-Munster (i-BFM) Study Group: Children and adolescents with follicular lymphoma have an excellent prognosis with either limited chemotherapy or with a "watch and wait" strategy after complete resection. Ann  Hematol 92: 1537-1541, 2013 (Contribution: Minor)
  17. Hui KF, Lam BH, Ho DN, Tsao SW, Chiang AKS: Bortezomib and SAHA synergistically induce ROS-driven caspase-dependent apoptosis of nasopharyngeal carcinoma and block replication of Epstein-Barr virus. Mol Cancer Ther 12: 747-758, 2013  (Contribution: Major)
  18. Lo CLR, Chan SC, Chan KL, Chiang AKS, Lo CM, Ng IOL: Post-transplant lymphoproliferative disorders in liver transplant recipients: a clinicopathological study. J Clin Pathol 66: 392-398, 2013 (Contribution: Minor)
  19. Surapolchai P, Ha SY, Chan GCF, Lukito JB, Wan, TSK, So, CC, Chiang AKS: Central diabetes insipidus: An unusual complication in a child with juvenile myelomonocytic leukemia and monosomy 7. J Pediatr Hematol Oncol 35: e84-e87, 2013 (Contribution: Major)
  20. Yang J, Cheuk DKL, Ha SY, Chiang AKS, Lee TL, Ho MH, Chan GCF: Infliximab for steroid refractory or dependent gastrointestinal acute graft-versus-host disease in children after allogeneic hematopoietic stem cell transplantation. Pediatr Transplant 16: 771-778, 2012 (Contribution: Minor)
  21. Leung AW, Vincent L, Chiang AKS, Lee AC, Cheng FW, Cheuk DK, Luk CW, Ling SC, Li CK: Prognosis and outcome of relapsed acute lymphoblastic leukemia: A Hong Kong Pediatric Hematology and Oncology Study Group Report. Pediatr Blood Cancer 59: 454-460, 2012 (Contribution: Major)
  22. Kwok H, Tong AH, Lin CH, Lok S, Farrell PJ, Kwong DL, Chiang AKS: Genomic sequencing and comparative analysis of Epstein-Barr virus genome isolated from primary nasopharyngeal carcinoma biopsy. PLoS One 7: e36939, 2012 (Contribution: Major)
  23. Hui KF, Ho DN, Tsang CM, Middeldorp JM, Tsao GSW, Chiang AKS: Activation of lytic cycle of Epstein-Barr virus by suberoylanilide hydroxamic acid leads to apoptosis and tumor growth suppression of nasopharyngeal carcinoma. Int J Cancer 131: 1930-1940, 2012 (Contribution: Major)
  24. Guo HX, Chan GCF, Chiang AKS, Ho MH, Chan EY, Ha SY: Dural sinus thrombosis owing to polycythaemia vera in a 12-year-old girl. Pediatr Int Child Health 32: 167-170, 2012 (Contribution: Minor)
  25. Duan YL, Ha SY, Loong F, Cheuk DKL, Chan GCF, Chiang AKS: Treatment of pediatric patient with stage Ⅳ extranodal natural killer/T-cell lymphoma, nasal type – A case report and literature review. Chin J Hematol 32: 701-703, 2011 (Contribution: Major)
  26. Ning RJ, Xu XQ, Chan KH, Chiang AKS: Long term carriers generate Epstein-Barr virus (EBV)-specific CD4+ and CD8+ polyfunctional T cell responses which show immunodominance hierarchies of EBV proteins. Immunology 134: 161-171, 2011 (Contribution: Major)
  27. Cheuk DKL, Chiang AKS, Lee TL, Chan GCF, Ha SY: Vaccines for prophylaxis of viral infections in patients with hematological malignancies. Cochrane Database Syst Rev 3: CD006505, 2011 (Contribution: Major)
  28. Gregorovic G, Bosshard R, Karlstegl CE, White RE, Pattle S, Chiang AKS, Dittrich-Breiholz O, Kracht M, Russ R, Farrell PJ: Cellular gene expression that correlates with EBER expression in Epstein-Barr virus-infected lymphoblastoid cell lines. J Virol 85: 3535-3545, 2011 (Contribution: Minor)
  29. Ha SY, Mok ASP, Chu WCW, Rasalkar DD, Cheuk DKL, Chiang AKS, Ho MHK, Chan GCF: Intermediate term evaluation of a practical chelation protocol based on stratification of thalassemic patients by serum ferritin and magnetic resonance imaging cardiac T2*. Hemoglobin 35: 199-205, 2011 (Contribution: Minor)
  30. Cheuk DKL, Chiang AKS, Chan GC, Ha SY: Urate oxidase for the prevention and treatment of tumor lysis syndrome in children with cancer. Cochrane Database Syst Rev 6: CD006945, 2010 (Contribution: Major)
  31. Ting JY, Chan SY, Lung DC, Ho AC, Chiang AKS, Ha SY, Tsoi NN, Chan GC: Intra-abdominal Rhizopus microsporus infection successfully treated by combined aggressive surgical, antifungal and iron chelating therapy. J Pediatr Hematol Oncol 32: e238-e240, 2010 (Contribution: Minor)
  32. Hui KF, Chiang AKS: Suberoylanilide hydroxamic acid induces viral lytic cycle in Epstein-Barr virus-positive epithelial malignancies and medicates enhanced cell death. Int J Cancer 126: 2479-2489, 2010 (Contribution: Major, Impact Factor: 4.572)
  33. Ha SY, Mok AS, Chu WC, Rasalkar DD, Cheuk DKL, Chiang AKS, Ho MH, Chan GCF: A practical chelation protocol based on stratification of thalassemic patients by serum ferritin and magnetic resonance imanging cardiac T2*. Hemoglobin 33: 323-331, 2009 (Contribution: Minor, Impact Factor: 1.274)
  34. Yuan XJ, Chan GCF, Chan SK, Shek TWH, Kwong DLW, Wei WI, Ha SY, Chiang AKS: Treatment outcome of rhabdomyosarcoma in Hong Kong Chinese children. HK Med J 14: 116-123, 2008 (Contribution: Major)
  35. Cheuk DKL, Mok SP, Lee AC, Chiang AKS, Ha SY, Lau YL, Chan GCF: Quality of life in patients with transfusion-dependent thalassemia after hematopoietic SCT. Bone Marrow Transplant 42: 319-327, 2008 (Contribution: Minor, Impact Factor: 3.000)
  36. Cheuk DKL, Shek TWH, Chan GCF, Lau YL, Ha SY, Chiang AKS: Parotid acinic cell carcinoma in a long-term survivor of childhood acute lymphoblastic leukemia. Pediatr Blood Cancer 50: 636-639, 2008 (Contribution: Major, Impact Factor: 2.164)
  37. Cheuk DKL, Lee TL, Chiang AKS, Ha SY, Chan GCF: Autologous hematopoietic stem cell transplantation for high-risk brain tumors in children. J Neurooncol 86: 337-347, 2008 (Contribution: Minor, Impact Factor: 2.477, Citation: 1)
  38. Chu SF, Tam CM, Wong HS, Kam KM, Lau YL, Chiang AKS: Association between RANTES functional polymorphisms and tuberculosis in Hong Kong Chinese. Genes Immun 8: 475-479, 2007 (Contribution: Major, Impact Factor: 4.088)
  39. Cheuk DKL, Wang P, Lee TL, Chiang AKS, Ha SY, Lau YL, Chan GCF: Risk factors and mortality predictors of hepatic veno-occlusive disease after pediatric hematopoietic stem cell transplantation. Bone Marrow Transplant 40: 935-944, 2007 (Contribution: Minor, Impact Factor: 3.000, Citation: 2)
  40. Cheuk DKL, Lee TL, Chiang AKS, Ha SY, Lau YL, Chan GCF: Risk factors and treatment of hemorrhagic cystitis in children who underwent hematopoietic stem cell transplantation. Transpl Int 20: 73-81, 2007 (Contribution: Minor, Impact Factor: 2.300, Citation: 6)
  41. Lee ACW, Lau YL, Li CH, Wong YC, Chiang AKS: Intraspinal and intracranial hemorrhage after lumbar puncture. Pediatr Blood Cancer 48: 233-237, 2007 (Contribution: Major, Impact Factor: 2.164)
  42. Wong OH, Huang FP, Chiang AKS: Differential responses of cord and adult blood-derived dendritic cells to dying cells. Immunology 116: 13-20, 2005 (Contribution: Major, Impact Factor: 3.398, Citation: 5)
  43. Tso HW, Ip WK, Chong WP, Tam CM, Chiang AKS, Lau YL: Association of interferon gamma and interleukin 10 genes with tuberculosis in Hong Kong Chinese. Genes Immun 6: 358-363, 2005 (Contribution: Major, Impact Factor: 4.088, Citation: 22)
  44. Chung BHY, Chan GCF, Lee TL, Kwok JSY, Chiang AKS, Ho HK, Ha SY, Lau YL: Chronic benign neutropenia among Chinese children. HK Med J 10: 231-236, 2004 (Contribution: Minor)
  45. Tso HW, Lau YL, Tam CM, Wong HS, Chiang AKS: Association of IL12B polymorphisms with tuberculosis in Hong Kong Chinese. J Infect Dis 190: 913-919, 2004 (Contribution: Major, Impact Factor: 3.066, Citations: 23)
  46. Ho HK, Chiang AKS, Kwong YL, Chan GCF, Lau YL, Ha SY: Pre-emptive treatment of early unstable mixed chimerism in a Chinese thalassaemia major patient by graded peripheral blood stem cell infusions. Haematologica 88: ECR03, 2003 (Contribution: Major, Impact factor: 1.352)
  47. Chan CW, Chiang AKS, Chan KH, Lau ASY: Epstein-Barr Virus-associated infectious mononucleosis in Chinese children. Pediatr Infect Dis J 22: 974-978, 2003 (Contribution: Major, Impact Factor: 3.086, Citation: 5)
  48. Chung BHY, Ha SY, Chan GCF, Chiang AKS, Lee TL, Ho HK, Lee CY, Luk CW, Lau YL: Klebsiella infection in patients with thalassaemia. Clin Infect Dis 36: 575-579, 2003 (Contribution: Minor, Impact Factor: 6.750)
  49. Chan KL, Fan ST, Tam PKH, Chiang AKS, Chan GCF, Ha SY: Paediatric hepatoblastoma and hepatocellular carcinoma: retrospective study. HK Med J 8: 13-17, 2002 (Contribution: Minor)
  50. Chan GCF, Chiang AKS, Ha SY, Lau YL, Ong JB, Lee ACW: Asparaginase-induced acute parotitis: an uncommon and self-limiting complication. Med Pediatr Oncol 39: 73-74, 2002 (Contribution: Major, Impact Factor: 1.278)
  51. Chan KL, Fan ST, Tam PKH, Chiang AKS, Chan GCF, Ha SY: Management of spontaneously ruptured hepatoblastoma in infancy. Med Pediatr Oncol 38: 137-138, 2002 (Contribution: Minor, Impact Factor: 1.278, Citations: 2)
  52. Ho HK, Ha SY, Lam CK, Chiang AKS, Chiu DSM, Chan GCF, Lau YL: Alloimmunization in Hong Kong Southern Chinese transfusion-dependent thalassemia patient. Blood 97: 3999-4000, 2001 (Contribution: Minor, Impact Factor: 10.896, Citations: 8)
  53. Shen L, Chiang AKS, Liu WP, Li GD, Liang RHS, Srivastava G: Expression of HLA class I, b2-microglobulin, TAP1 and IL-10 in Epstein-Barr virus-associated nasal NK/T-cell lymphoma: implications for tumor immune escape mechanism. Int J Cancer 92: 692-696, 2001 (Contribution: Major, Impact Factor: 4.512, Citations: 17)
  54. Chiang AKS, Chan GCF, Ma SK, Ng YK, Ha SY, Lau YL: Disseminated fungal infection associated with myeloperoxidase deficiency in a premature neonate. Pediatr Infect Dis J 19: 1027-1029, 2000 (Contribution: Major, Impact Factor: 3.086, Citations: 2)
  55. Srivastava G, Wong KY, , Lam KY, Tao Q: Coinfection of multiple strains of Epstein-Barr virus in immunocompetent normal individuals: reassessment of the viral carrier state. Blood 95: 2443-2445, 2000 (Contribution: Major, Impact Factor: 10.896, Citations: 32)

 

B. (Journal papers/Articles; Regional and Local)

  1. Xiong H, Ha SY, Chiang AKS, Hu Q, Chan GCF.  A small cohort review of the long-term prognosis for Chinese older children and adolescents with acute lymphoblastic leukaemia treated on a paediatric protocol.  HK J Paediatr 18: 89-95, 2013 (Contribution: Minor)
  2. Surapolchai P, Ha SY, Chiang AKS, Cheuk DKL, Li CH, So CC, Wan TSK, Chan GCF: Challenges in the management of juvenile myelomonocytic leukaemia in Hong Kong over the past two decades. HK J Paediatr 17:148-155, 2012 (Contribution: Major)
  3. Xiong H, Ha SY, Chiang AKS, Cheuk DKL, Zeng LK, Chan GCF: A small cohort review of neonatal transient myeloproliferative disease in Chinese children. HK J Paediatr 16: 258-263, 2011 (Contribution: Minor)
  4. Zhang ZQ, Chan GCF, Lam CCK, So JCC, Cheuk DKL, Chiang AKS, Ha SY: The clinical features of Chinese children with von Willebrand disease: The experience of a tertiary institute. HK J Paediatr 16: 95-100, 2011 (Contribution: Minor)
  5. Xiong H, Ha SY, Chiang AKS, Lau YL, Hu Q, Chan GCF: Reversible leukoencephalopathy following intrathecal methotrexate. HK J Paediatr 15: 327-331, 2010 (Contribution: Minor)
  6. Lam DST, Khong PL, Chiang AKS, Ha SY, Chan GCF: Reversible encephalopathy induced by systemic high dose methotrexate. HK J Paediatr 12: 287-292, 2007 (Contribution: Minor)
  7. Chiang AKS: Two pediatric liver cancers respond very differently to chemotherapy. Oncology Times XXXVIII (11): 26, 2006 (Contribution: Major)
  8. Chung BHY, Lee TL, Chan GCF, Chiang AKS, Chan KW, Ha SY, Lau YL: Haematopoietic stem cell transplant for Wiskottt-Aldrich syndorome. HK J Paediatr 11: 186-190, 2006 (Contribution: Minor)
  9. Pesquera-Lepatan LM, Chan GCF, Lam C, Ho MHK, Lee TL, Chiang AKS, Ha SY, Lau YL: Cerebral Infarction in Childhood Acute Lymphoblastic Leukaemia Treated with Low Dose E. coli Asparaginase. HK J Paediatr 11: 69-72, 2006 (Contribution: Minor)
  10. Ho MHK, Chan GCF, Jones BM, Lee TL, Chiang AKS, Ha SY, Lau YL: Juvenile Pernicious Anaemia in Association with Vitiligo, Selective IgA Deficiency, Defective Interleukin 12 Production and T Cell Dysfunction. HK J Paediatr 11: 59-63, 2006 (Contribution: Minor)
  11. Ha SY, Chan GCF, Chiang AKS, Lee ACW, Lee TL, Lau YL: Bone Marrow Transplantation for Fanconi Anaemia Using a Fludarabine-based Preparative Regimen with CD34+ Cell Selection. HK J Paediatr 11: 39-44, 2006 (Contribution: Minor)
  12. Cheuk DKL, Lee TL, Ha SY, Chan GCF, Lau YL, Chiang AKS: Bone Marrow Transplantation for Hepatitis-associated Aplastic Anaemia: Case Reports and a Review of the Literature. HK J Paediatr 11: 32-38, 2006 (Contribution: Major)
  13. Lobo RCM, Chan GCF, Lee TL, Chiang AKS, Ho HK, Ha SY, Lau YL: X-linked agammaglobulinaemia in Hong Kong Chinese. HK J Paediatr 8: 15-20, 2003 (Contribution: Minor)
  14. Cheuk KL, Chiang AKS: Case study: An 11-year old boy with good past health presented with malaise, repeated vomiting, fever and dark urine for a week. Medical Tribune: Oct 2002 (Contribution: Major)

 

C. (Conference Papers; International and Regional)

  1. Chiang ASK, Huang Shuang, Chung HY, Cheuk DKL, Ha SY, Chan GCF: Epidemiology and outcome of post-transplant iymphproliferative disorder in pediatric liver transplant recipients. Fifth International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin Lymphoma, Varese, Oct 22-24, 2015 (post presentation).
  2. Pillon M, Carraro E, Osumi T, Fedorova A, Lavoine N, Barzilai-Birenboim S, Csoka M, Loeffen J, Chiang AKS, Jazbec J, Kabickova E, Bubanska E, Uyttebreck A, Wrobel G, O Abla, Krenova Z, Lazic J, Burkhardt B, Attarbaschi A: Characteristics and outcome of children and adolescents with constitutional conditions suffering from Non-Hodgkin’s Iymphoma. Fifth International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin Lymphoma, Varese, Oct 22-24, 2015 (post presentation).
  3. Yeung PL, Hui KF, Chiang AKS: Combination of histone deacetylase and proteasome inhibitors induces enhanced killing cells through suppression of the function of EBNA-3c protein. Fifth International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin Lymphoma, Varese, Oct 22-24, 2015 (poster discussion session)
  4. Mellgren K, Chiang AKS, Abla O, Alexander A, Plat G, Myakova N, Meyer-Wentrup F, Kobayashi R, Pillon M, Bubanska E, Kabickova E, Krenova Z, Fedorova A, Wrobel G, Klapper W, Klapper D, Williams D, Attarbaschi A, Kontny U: Non-anaplastic peripheral T-cell lymphoma in children and adolescents - International review. Fifth International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin Lymphoma, Varese, Oct 22-24, 2015 (oral  presentation).
  5. Chiang AKS, Yeung PL, Hui KF: Targeting EBV in EBV-associated malignancies. Keystone Symposia Conference - Viruses and Human Cancer, Montana, USA, Mar 29-Apr 3, 2015, (poster and oral presentation).
  6. Yeung PL, Hui KF, Leung YY, Chiang AKS: Combination of HDAC and proteasome inhibitors up-regulates p16INK4A and p21WAF1 and induces apoptosis of EBV-transformed lymphoblastoid cell lines. 16th International Symposium on EBV and Associated Diseases, Brisbane, Australia, Jul 16-19, 2014 (poster presentation).
  7. Wong AMG, Ning RJ, Chan KH, Chiang AKS: Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr virus in paediatric liver transplant recipients who developed post-transplant lymphoproliferative disorder. 16th International Symposium on EBV and Associated Diseases, Brisbane, Australia, Jul 16-19, 2014 (poster presentation).
  8. Choi CK, HO DN, Hui KF, Kao RYT, Chiang AKS: Identification of novel small organic compounds for induction of Epstein-Barr virus (EBV) lytic cycle in EBV-positive epithelial malignancies. 16th International Symposium on EBV and Associated Diseases, Brisbane, Australia, Jul 16-19, 2014 (poster presentation).
  9. Chiang AKS, Ning RJ, Chan KH: Emergence of highly functional antigen-specific T cells towards Epstein-Barr virus corresponds to viral control and enhanced cytotoxicity in children with infectous mononucleosis and primary asymptomatic infection. 16th International Symposium on EBV and Associated Diseases, Brisbane, Australia, Jul 16-19, 2014 (poster presentation).
  10. Chiang AKS, Kwok H, Wu CW, Palser AL, Kellam P, Sham PC, Kwong DLW: Genomic diversity of Epstein-Barr virus genomes isolated from primary nasopharyngeal carcinoma biopsies. 16th International Symposium on EBV and Associated Diseases, Brisbane, Australia, Jul 16-19, 2014 (oral presentation).
  11. Hui KF, Choi Ck, Yeung PL, Middeldorp JM, Tsao GSW, Chiang AKS: Inhibition of class I histone deacetylases (HDACs) by HDAC inhibitiors leads to the induction of Epstein-Barr virus (EBV) lytic cycle in EBV-positive epithelial malignancies. 16th International Symposium on EBV and Associated Diseases, Brisbane, Australia, Jul 16-19, 2014 (oral presentation).
  12. Chiang AKS, Hui KF: Proteasome inhibitor synergizes with histone deacetylase inhibitor to trigger ROS- and ER stress-induced apoptosis of nasopharyngeal carcinoma independent of aggresome disruption, AACR Annual Meeting 2014, San Diego, USA, Arp 5-9, 2014 (poster presentation).
  13. Hui KF, Leung YY, Yeung PL, Chiang AKS: Combination of Suberoylanilide Hydroxamic Acid and Brotezomib Synergistically Induces Apoptosis of EBV-Positive Burkitt Lymphoma Cells of Wp-Restricted or Type III Latency. EBV 50th Anniversary, Oxford, UK, Mar 23-25, 2014 (poster presentation).
  14. Chan GCF, Shing MK, Luk CW, Li RCH, Ling SC, Cheuk DKL, Lee VSW, Yuen HL, Lee ACW, Li CK, Chiang AKS: Brain tumors of children <18-month-old: A population based study. 45th Congress of the International Society of Paediatric Oncology, Hong Kong, Sep 25-28, 2013 (poster presentation).
  15. Chan GCF, Shing MK, Luk CW, Li RCH, Ling SC, Cheuk DKL, Lee VWS, Yuen HL, Lee ACW, Li CK, Chiang AKS: Uncommon types of brain tumors among Chinese children. 45th Congress of the International Society of Paediatric Oncology, Hong Kong, Sep 25-28, 2013 (poster presentation).
  16. Chiu SY, Chan HY, Shum SK, Cheuk DKL, Chiang AKS, Ha SY, Chan GCF: Treatment of children with drug-resistant graft-versus-host-disease by extracorporeal photopheresis. 45th Congress of the International Society of Paediatric Oncology, Hong Kong, Sep 25-28, 2013 (poster presentation).
  17. Hung CY, Chiu SY, Shum SK, Chan HY, Cheuk DKL, Chiang AKS, Ha SY, Chan GCF: Surveillance on central venous catheter complications in paediatric haematology oncology unit. 45th Congress of the International Society of Paediatric Oncology, Hong Kong, Sep 25-28, 2013 (poster presentation).
  18. Lee V, Luk CW, Cheuk DKL, Li CH, Ling SC, Leung AWK, Yuen HL, Chiang AKS, Shing MMK: Long term treatment outcome of conventional high grade osteosarcoma in Hong Kong children and adolescents – from the Hong Kong paediatric haematology and oncology study group. 45th Congress of the International Society of Paediatric Oncology, Hong Kong, Sep 25-28, 2013 (poster presentation).
  19. Yu JL, Khong PL, Chiang AKS, Cheuk DKL, Ha SY, Chan GCF: Cystic-like liver tumours in children: two diseases with similar appearance but required different treatment approach. 45th Congress of the International Society of Paediatric Oncology, Hong Kong, Sep 25-28, 2013 (poster presentation).
  20. Chiang AKS, Lee V, Yuen H, Li C, Ling S, Cheuk DKL, Lee AC: Results of a uniform treatment protocol based on the FAB/LMB96 study for B cell non-hodgkin lymphoma in children and adolescents of Hong Kong. 45th Congress of the International Society of Paediatric Oncology, Hong Kong, Sep 25-28, 2013 (poster presentation).
  21. Chiang AKS, Lee V, Yuen H, Li C, Ling S, Cheuk DKL, Lee AC: Results of a uniform treatment protocol based on the ALCL99 study for anaplastic large cell lymphoma in children and adolescents of Hong Kong. 45th Congress of the International Society of Paediatric Oncology, Hong Kong, Sep 25-28, 2013 (poster presentation).
  22. Chiang AKS, Cheuk DKL, Ha SY, Chan GCF: Treatment outcome of post-transplant lymphoproliferative disorder in paediatric liver transplant recipients using rituximab-based regimen. 45th Congress of the International Society of Paediatric Oncology, Hong Kong, Sep 25-28, 2013 (poster presentation).
  23. Chiang AKS, Ling S, Li C, Yuen H, Li C, Cheuk DKL, Li C: Population-based treatment results of hepatoblastoma in children of Hong Kong. 45th Congress of the International Society of Paediatric Oncology, Hong Kong, Sep 25-28, 2013 (poster presentation).
  24. Attarbaschi A, Beishuizen A, Mann G, Rosolen A, Mori T, Uyttebroeck A, Niggli F, Csoka M, Krenova Z, Mellgren K, Kabickova E, Chiang AKS, Reiter A, Williams D, Burkhardt B: Children and adolescents with follicular lymphoma have an excellent prognosis with either limited chemotherapy or with a “watch and wait” strategy after complete resection. 45th Congress of the International Society of Paediatric Oncology, Hong Kong, Sep 25-28, 2013 (poster presentation).
  25. Cheuk DKL, Chiang AKS, Ha SY, Chan GCF: Improving outcomes of hematopoietic stem cell transplant for pediatric acute lymphoblastic leukemia in Hong Kong. 45th Congress of the International Society of Paediatric Oncology, Hong Kong, Sep 25-28, 2013 (poster presentation).
  26. Cheuk DKL, Chiang AKS, Ha SY, Chan GCF: Favorable outcomes of unrelated cord blood transplant for pediatric acute myeloid leukemia in Hong Kong. 45th Congress of the International Society of Paediatric Oncology, Hong Kong, Sep 25-28, 2013 (poster presentation).
  27. Yuen ANY, Ho SMY, Chan CKY, Chiang AKS, Lee V, Yuen HL, Ling SC: The relationship between hope, rumination response styles, rumination content and psychological adjustment among childhood cancer patients and survivors. 45th Congress of the International Society of Paediatric Oncology, Hong Kong, Sep 25-28, 2013 (poster presentation).
  28. Xiong H, Ha SY, Chiang AKS, Cheuk DKL, Li H, Chan GCF: Outcome of hematopoietic stem cell transplantation in refractory / relapsed infant leukemia. 45th Congress of the International Society of Paediatric Oncology, Hong Kong, Sep 25-28, 2013 (poster presentation).
  29. Chiang AKS, Godzinski J: Free Paper Session 24 – Renal and Sarcomas III. 45th Congress of the International Society of Paediatric Oncology, Hong Kong, Sep 25-28, 2013 (chair session).
  30. Attarbaschi A, Mann G, Rosolen A, Horibe K, Uyttebroeck A, Beishuizen A, Niggli F, Csoka M, Krenova Z, Melgren K, Kabickova E, Chiang AKS, Reiter A, Williams D, Burkhardt B: Clinical characterisitics and outcome of pediatric and adolescent patients with follicular lymphoma – The EICNHL and i-BFM study groups experience. Fourth International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin’s Lymphoma, New York, USA, Nov 1-3, 2012
  31. Hui KF, Lam BHW, Ho DN, Chiang AKS: Bortezomib combines with suberoylanilide hydroxamic acid (SAHA) to synergistically induce caspase-dependent apoptosis and blocks SAHA’s activation of EBV lytic cycle in nasopharyngeal carcinoma. International Congress on Oncogenic Herpesviruses and Associated Diseases, Philadelphia, USA, Aug 1-4, 2012
  32. Chiang AKS, Hui KF: Activation of lytic cycle of Epstein-Barr virus by suberoylanilide hydroxamic acid effects apoptosis and tumor growth suppression of nasopharyngeal carcinoma. 103rd Annual Meeting of American Association for Cancer Research, Chicago, USA, Mar 31 - Apr 4, 2012
  33. Robles JDF, Cheuk DanielKL, Ha SY, Chiang AKS, Chan GCF: Norovirus infection in post-hematopoietic stem cell transplant children: a four-year experience at Queen Mary Hospital in Hong Kong. St. Jude Asia Forum, Singapore, Mar, 2012
  34. Ning RJ, Chiang AKS: Long term viral carriers generate T cells of higher functionality than pateints with posttransplant lymphoproliferative disorder. Cold Spring Harbor Asia Symposium on Infection and Immunology, Suzhou, China, Sep 8-12, 2011
  35. Chiang AKS, Hui KF: Targeting Epstein-Barr virus lytic cycle induction in nasopharyngeal carcinoma by suberoylanilide hydroxamic acid. American Society of Biochemistry and Molecular Biology (ASBMB) 2011 Special Symposium on Recent Advances in Pathogenic Human Viruses, Guangzhou, China, Jul 24-26, 2011 (oral presentation)
  36. Cheuk DKL, Chiang AKS, Ha SY, Chan GCF: Outcomes of osteosarcoma in children: Experience of Queen Mary Hospital. 4th National Pediatric Surgical Oncology Conference and 4th Cross Strait Symposium on Pediatric Oncology, LKS Faculty of Medicine, The University of Hong Kong and Children’s Cancer Foundation, Hong Kong, Nov 5-6, 2010
  37. Chiang AKS: Diagnosis and treatment of paediatric non-Hodgkin lymphomas. 4th National Pediatric Surgical Oncology Conference and 4th Cross Strait Symposium on Pediatric Oncology, LKS Faculty of Medicine, The University of Hong Kong and Children’s Cancer Foundation, Hong Kong, Nov 5-6, 2010
  38. Cheuk DKL, Chiang AKS, Ha SY, Chan GCF: Ewing sarcoma family of tumors in children: experience of Queen Mary Hospital. 4th National Pediatric Surgical Oncology Conference and 4th Cross Strait Symposium on Pediatric Oncology, LKS Faculty of Medicine, The University of Hong Kong and Children’s Cancer Foundation, Hong Kong, Nov 5-6, 2010
  39. Hui KF, Tsang CM, Tsao GSW, Chiang AKS: Suberoylanilide hydroxamic acid mediates enhanced apoptosis in nasopharyngeal carcinoma through induction of Epstein-Barr virus lytic cycle and activation of caspase-3. The 14th Biennial Conference of the International Association for Research on Epstein-Barr Virus & Associated Diseases, University of Birmingham, UK, Sep 4-7, 2010
  40. Kwok H, Chiang AKS: Comparative analysis of Epstein-Barr virus (EBV) latent gene and microrna sequences among AKATA, B95.8, AG876 and GD1 EBV genomes. The 14th Biennial Conference of the International Association for Research on Epstein-Barr Virus & Associated Diseases, University of Birmingham, UK, Sep 4-7, 2010
  41. Ho DN, Hui KF, Chiang AKS: Kinetics of Epstein-Barr virus (EBV) latent and lytic protein expression in EBV-positive burkitt, epithelial and lymphoblastoid cells upon induction of lytic cycle. The 14th Biennial Conference of the International Association for Research on  Epstein-Barr Virus & Associated Diseases, University of Birmingham, UK, Sep 4-7, 2010
  42. Ning RJ, Xu XQ, Chiang AKS: Analysis of CD4+ and CD8+ Epstein-Barr virus-specific polyfunctional T cell responses in Chinese long term carriers by a novel 9-colour flow cytometric assay. The 14th Biennial Conference of the International Association for Research on  Epstein-Barr Virus & Associated Diseases, University of Birmingham, UK, Sep 4-7, 2010
  43. Hui KF, Tsao GS, Chiang AKS: Suberoylanilide hydroxamic acid induces Epstein-Barr virus lytic cycle and enhanced apoptosis in nasopharyngeal carcinoma. 101st Annual Meeting of American Association for Cancer Research, Washington DC, USA, Apr 17-21, 2010
  44. Chiang AKS: Young boy presenting with 1-week history of high fever and dark-coloured urine. 3rd International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin’s Lymphoma, Frankfurt, Germany, Jun 11-13, 2009 (oral presentation) [Abstract published in Haematology Meeting Reports 2009; 3(5): 92]
  45. Chiang AKS: Adolescent girl presenting with persistent and enlarging skin ulcers in her leg. 3rd International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin’s Lymphoma, Frankfurt, Germany, Jun 11-13, 2009 (oral presentation) [Abstract published in Haematology Meeting Reports 2009; 3(5): 92]
  46. Chiang AKS, Ha SY, Chan GCF: Clinical features and treatment results of post-transplant lymphoproliferative disorder following orthotopic liver transplantation in Chinese children. 3rd International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin’s Lymphoma, Frankfurt, Germany, Jun 11-13, 2009 [Abstract published in Haematology Meeting Reports 2009; 3(5): 92],
  47. Lee TL, Ho MHK, Lee PPW, Cheuk DKL, Chan GCF, Chiang AKS, Ha SY, Lau YL: Hematopoietic stem cell transplantation for primary immunodeficiencies: Queen Mary Hospital experience from 1992 to 2008.  2009 Chinese Blood and Marrow Transplantation Forum and Annual Scientific Meeting of Hong Kong Society of Haematology, Hong Kong, Feb 27 - Mar 2, 2009
  48. Ha SY, Chan GCF, Kwok JSY, Chiang AKS, Lee TL, Lau YL: Matched unrelated donor transplantation for Hong Kong patients with thalassemia major. 2009 Chinese Blood and Marrow Transplantation Forum and Annual Scientific Meeting of Hong Kong Society of Haematology, Hong Kong, Feb 27 - Mar 2, 2009
  49. Ha SY, Chan GCF, Chiang AKS, Lee TL, Lau YL: Treatment outcome is comparable with either sibling cord blood or bone marrow for transplantation in transfusion dependent thalassaemic patients using a standardized conditioning regimen. 2009 Chinese Blood and Marrow Transplantation Forum and Annual Scientific Meeting of Hong Kong Society of Haematology, Hong Kong, Feb 27 - Mar 2, 2009
  50. Zhu GH, Chan GCF, Chiang AKS, Lee TL, LauYL, Ha SY: Outcome of hematopoietic stem cell transplantation for malignant infantile osteopetrosis. 2009 Chinese Blood and Marrow Transplantation Forum and Annual Scientific Meeting of Hong Kong Society of Haematology, Hong Kong, Feb 27 - Mar 2, 2009
  51. Chiang AKS: Treatment of posttransplant lymphoproliferative disorder presenting as protracted infectious mononucleosis with rituxmab. 50th ASH Annual Meeting and Exposition, San Francisco, California, USA, Dec 6-9, 2008
  52. Kwok H, Chan KW, Chiang AKS: Discordant Epstein-Barr Virus (EBV) strains in plasma, peripheral blood mononuclear cells and saliva of children with primary EBV infection. The 13th Biennial Conference of the International Association for Research on Epstein-Barr Virus and Associated Diseases, Guangzhou, China, Nov 7-10, 2008
  53. Xu Xuequn, Chan KH, Chiang AKS: Development of polychromatic flow cytometry assay to study polyfunctional Eptsein-Barr Virus (EBV)-specific CD8+ cytotoxic T-lymphocyte responses. The 13th Biennial Conference of the International Association for Research on Epstein-Barr Virus and Associated Diseases, Guangzhou, China, Nov 7-10, 2008
  54. Hui KF, Chiang AKS:  Suberoylanidide hydroxamic acid (SAHA) induces viral lytic cycle in Epstein-Barr Virus (EBV) – infected gastric carcinoma cells and mediates enhanced cell death. The 13th Biennial Conference of the International Association for Research on Epstein-Barr Virus and Associated Diseases, Guangzhou, China, Nov 7-10, 2008
  55. Chiang AKS: 鼻NK/T細胞淋巴瘤: EB病毒基因表達和免疫逃逸機制. 第十四屆全國小兒血液病學術會議, Wuhan, China, Oct 10-Nov 1, 2008
  56. Chiang AKS: Paediatric lymphomas: subtypes and treatment strategies. The National Continuing Medical Education Class - Hot-points and Difficulties in the Clinical Research of Pediatric Hematology/Oncology Disease, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China, May 12-16, 2008
  57. Chiang AKS: Epstein-Barr Virus and Lymphoproliferative diseases, The National Continuing Medical Education Class - Hot-points and Difficulties in the Clinical Research of Pediatric Hematology/Oncology Disease, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China, May 12-16, 2008
  58. Chiang AKS: Contemporary treatment of paediatric lymphoma, 第三屆廣東省小兒腫瘤學術研討會, Guangzhou, China, Dec 8, 2007
  59. Ha SY, Mok SP, Chu WCW, Rasalkar DD, Cheuk KL, Chiang AKS, Ho MHK, Chan GCF: A practical chelation protocol based on stratification of thalassemic patients by serum ferritin and MRI cardiac T2*. 17th International Conference on Chelation (ICOC) for the treatment of thalassaemia, cancer and other diseases related to metal and free radical imbalance and toxicity, Shenzhen, China, Nov 23-26, 2007
  60. Ha SY, Cheuk DKL, Ho MHK, Chiang AKS, Chan GCF: Experience in Chelation Regimens adjusted According To Categorisation of Trancfusing-Dependent Thalassemic Patients Using Serium Ferritin and MRI Data. 17th International Conference on Chelation (ICOC) for the treatment of thalassaemia, cancer and other diseases related to metal and free radical imbalance and toxicity, Shenzhen, China, Nov 23-26, 2007
  61. Cheuk DKL, Au WY, Ho MHK, Chiang AKS, Chan GCF, Ha SY: Neutropenia and Agranulocytosis Associated with the Use of Deferiprone in Patients with Thalassemia Major: The Expeerience of Queen Mary Hospital in Hong Kong. 17th International Conference on Chelation (ICOC) for the treatment of thalassaemia, cancer and other diseases related to metal and free radical imbalance and toxicity, Shenzhen, China, Nov 23-26, 2007
  62. Chiang AKS, Yuan XJ: Treatment outcome and adverse factors of rhabomyosarcoma in Hong Kong Chinese children. 39th Annual Congress of the International Society of Paediatric Oncology (SIOP 2007), Mumbai, India, Nov 1-3, 2007 [Abstract published in Official Journal of the International Society of Paediatric Oncology P. 488 (PD.118), 2007]
  63. Chung BHY, Lee TL, Chan GCF, Chiang AKS, Chan KW, Ha SY, Lau YL: Haematopoietic stem cell transplant for Wiskott-Aldrich syndrome. 2nd Congress of Asian Society for Pediatric Research (ASPR), Yokohama, Japan, Dec 8-10, 2006
  64. Chiang AKS: An unusual case of rapidly progressing obstructive jaundice in an 18 year old male. Masterclass in Paediatric Oncology, The European School of Oncology, Milan, Italy, Oct 14-18, 2006 (oral presentation)
  65. Chiang AKS: Treatment outcome of hepatoblastoma and hepatocellular carcinoma in Hong Kong children. Second Cross Strait Symposium on Pediatric Oncology, Taiwan, Sep 21-23, 2006
  66. To KW, Wong OH, Li HB, Chen SF, Lo CK, Chiang AKS, Huang FP: Effects of Bergapten on Dendritic Cell Functions. 9th International Syposium on Dendritic Cells, Edinburgh, England, Sep 16-20 , 2006
  67. To KW, Wong OH, Li HB, Chen SF, Lo CK, Chiang AKS, Huang FP: Immunomodulatory effects of Bergapten on dendritic cell function. 9th International Conference on Dendritic Cell, Edinburgh, England, Sep16-20, 2006
  68. Chiang AKS, KH Chan: Comparison of serological and virological parameters between infectious mononucleosis and asymptomatic primary Epstein-Barr Virus infection. 12th Biennial Conference of the International Association for Research on Epstein-Barr Virus and Associated Diseases (EBV 2006), Boston, USA, Jul 8-12, 2006
  69. Chiang AKS, Lee ACW, Shing MMK, Yuen HL, Li CK: Treatment outcome of lymphoblastic lymphomas in children in Hong Kong. Second International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin’s Lymphoma, New York, USA, May 18-20, 2006
  70. Chiang AKS, Lee PPW, Li CK, Yuen HL, Lee ACW, Li CK: Treatment outcome of hepatocellular carcinoma and hepatoblastoma in children in Hong Kong. 4th Congress of the International Society of Pediatric Oncology-Asia, Shanghai, China, Apr 6-8, 2006 (oral presentation)
  71. Cheuk DKL, Lee ACW, Chiang AKS, Ho HK, Ha SY, GCF Chan, Lau YL: Quality of life study on transfusion: Dependent thalassaemic patients in Hong Kong. 10th International Conference on Thalassaemia & Haemoglobinopathies & 12th International TIF Conference for Thalassaemia Patients and Parents, Dubai, United Arab Emirates, Jan 7-10, 2006
  72. Chiang AKS: Infectious mononucleosis in Hong Kong Chinese children. Symposium on Epstein Barr Virus – associated chronic active infection and hemophagocytic syndrome, National Health Research Institutes, Chunan, Taiwan, Oct 10, 2005
  73. Lee ACW, Chiang AKS, Shing MMK, Yuen HL, Li CK: Treatment of paediatric non-Hodgkin’s Lymphoma: a report of the Hong Kong Paediatric Haematology & Oncology Study Group. World Congress of the International Society of Haematology, Istanbul, Turkey, Sep 28-Oct 2, 2005 [Abstract published in Turkish Journal of Haematology 22 (Supplement): 245, 2005]
  74. Chiang AKS, Wong OH, Huang F: Functional Comparison of Cord and Adult Blood-Derived Dendritic Cells, 1st Annual Fall Conference of the Journal of Pediatric Haematology Oncology, Vancouver, Canada, Sep19-22, 2005
  75. Chu SF, Ng MW, Tam CM, Kam KM, Song YQ, Lau YL, Chiang AKS: Association of the MCP-1 promoter polymorphism with tuberculosis in the Hong Kong Chinese population. European Human Genetics Conference 2005, Prague, Czech Republic, May 7-10, 2005 [Abstract published in Eur J Hum Genet 13 (Suppl 1): 299, 2005]
  76. Chiang AKS, Wong OH, Huang FP: Differential responses of cord and adult blood-derived dentritic cells to dying cells. Cellular and Molecular Immunology C95, The 3rd Congress of the Federation of Immunology Societies of Asia-Oceania, Chinese Society of Immunology, Hangzhou, China, Apr 18-22, 2005 (oral presentation)
  77. Chiang AKS, Chan GCF, Ha SY, Chan KH: Respiratory syncytial virus (RSV) infections in immunocompromized children. 46th Annual Meeting of the American Society of Hematology, San Diego, USA, Dec 4-7, 2004 [Abstract published in Blood 104 (No.11, Suppl. 2): 410b, 2004]
  78. Chiang AKS, Chan CW, Lee PPW, Chan KH: Epstein-Barr virus-associated infectious mononucleosis in Chinese children. The 11th Biennial Conference of the International Association for Research on Epstein-Barr Virus and Associated Diseases, Regensburg, Germany, Sep 20-25, 2004
  79. Chiang AKS, Lam SY, Chan KH: Kinetics of EBV-specific antibody responses in symptomatic and asymptomatic primary Epstein-Barr virus infection in Chinese children. The 11th Biennial Conference of the International Association for Research on Epstein-Barr Virus and Associated Diseases, Regensburg, Germany, Sep 20-25, 2004
  80. Wong OH, Huang F, Chiang AKS: Role of dendritic cell in the immune regulation of primary Epstein-barr virus infection. 12th International Congress of Immunology, Montreal, Canada, Jul 18-23, 2004
  81. Lee TL, Chan GCF, Ha SY, Ho MHK, Chiang AKS, Lau YL: Autologous stem cell transplant in 3 patients with refractory autoimmune diseases. 45th Annual Meeting of the American Society of Hematology, San Diego, California, USA, Dec 6-9, 2003 [Abstract published in Blood 102 (no.11, suppl. 2): #5667, 2003]
  82. Tso HW, Lau YL, Tam CM, Chiang AKS: Association of interleukin 12B genetic polymorphisms with tuberculosis in Chinese. The Genome of Homo Sapiens, 68th Cold Spring Harbor Symposium on Quantitative Biology, Cold Spring Harbor Laboratory, New York, USA, May 28 - Jun 2, 2003
  83. Chiang AKS, Chan D, Chan KH, Lau ASY: Epstein-Barr virus associated infectious mononucleosis in Chinese children. First International Symposium on Childhood and Adolescent non-Hodgkin’s Lymphoma, New York, USA, Apr 10-12, 2003
  84. Chiang AKS, Ma SK, Jones BM, Li YH, Chan GCF, Ha SY, Lau YL: Long term immune reconstitution and cell lineage chimerism after bone marrow transplantation for severe combined immunodeficiency and Wiskott-Aldrich syndrome. 44th Annual Meeting of the American Society of Hematology, Philadelphia, USA, Dec 6-10, 2002 [Abstract published in Blood 100 (No. 11, Suppl. 2): 457b, 2002]
  85. Chiang AKS: Recombinant adenovirus-transduced expression of CD40 and CD40 ligand in dendritic cells. 7th International Symposium on Dendritic Cells, Bamberg, Germany, Sep 19-24, 2002
  86. Chiang AKS, Chan GCF, Ha SY, Ho HK, Lee TL, Lau YL: Characteristics and treatment outcome of childhood Burkitt lymphomas in Hong Kong Chinese children. 23rd International Congress of Pediatrics, Beijing, China, Sep 9-14, 2001
  87. Chan GCF, Chan KL, Kwong DLW, Chiang AKS, Lee TL, Ha SY, Tam PKH, Lau YL: Malignant tumours in the head and neck region in childhood: good outcome with current therapeutic approach. 23rd International Congress of Pediatrics, Beijing, China, Sep 9-14, 2001
  88. Chan KL, Fan ST, Chiang AKS, Chan GCF, Ha SY: Management of spontaneously ruptured hepatoblastoma in infancy. 23rd International Congress of Paediatrics, Beijing, China, Sep 9-14, 2001
  89. Ho HK, Chan GCF, Lee TL, Chiang AKS, Ha SY and Lau YL: Childhood rhadomyosarcoma: experience of a single institution in Hong Kong. The 3rd Chinese National Pediatric Cancer Study Group Conference, Guangdong, China, May 15-20, 2001

 

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